Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 11/20 | 0.77 |
| ▸ | DRD2 | P14416 | 3/20 | 0.59 |
| ▸ | DRD3 | P35462 | 3/20 | 0.59 |
| ▸ | HTR1A | P08908 | 2/20 | 0.57 |
| ▸ | HTR7 | P34969 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5261357 | 0.87 | HRH3 (1.00) | HRH3DRD2DRD3HTR1AHTR7 | |
| SCHEMBL6421374 | 0.86 | HRH3 (0.98) | HRH3DRD2DRD3HTR1AHTR7 | |
| SCHEMBL6421371 | 0.85 | HRH3 (0.84) | HRH3DRD2DRD3HTR1AHTR7 | |
| SCHEMBL5416238 | 0.84 | HRH3 (1.00) | HRH3DRD2DRD3ALDH1A1KDM4E | |
| SCHEMBL6421382 | 0.79 | HRH3 (0.73) | HRH3DRD2DRD3HTR1AHTR7 | |
| SCHEMBL4295616 | 0.78 | HRH3 (1.00) | HRH3ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL8086599 | 0.75 | DRD3 (1.00) | HRH3DRD2DRD3HTR1AHTR7 | |
| SCHEMBL11020028 | 0.73 | ALDH1A1 (0.85) | HRH3ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL19322165 | 0.73 | PDE5A (0.60) | HRH3DRD2DRD3ALDH1A1KDM4E | |
| SCHEMBL8086583 | 0.72 | DRD2 (1.00) | HRH3DRD2DRD3HTR1AHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6908929-B2 | Phenyl-substituted imidazopyridines | ORTHO-MCNEIL PHARMACEUTICAL, INC. (US) | 2005-06-21 | — | — | US | claimed |