Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 18/20 | 0.73 |
| ▸ | DRD2 | P14416 | 2/20 | 0.52 |
| ▸ | DRD3 | P35462 | 2/20 | 0.52 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.52 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.52 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.52 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.52 |
| ▸ | HTR1A | P08908 | 1/20 | 0.52 |
| ▸ | HTR7 | P34969 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6421371 | 0.89 | HRH3 (0.84) | HRH3DRD2DRD3HTR1AHTR7 | |
| SCHEMBL5261357 | 0.84 | HRH3 (1.00) | HRH3DRD2DRD3HTR1AHTR7 | |
| SCHEMBL6421374 | 0.83 | HRH3 (0.98) | HRH3DRD2DRD3HTR1AHTR7 | |
| SCHEMBL6421366 | 0.79 | HRH3 (0.77) | HRH3DRD2DRD3HTR1AHTR7 | |
| SCHEMBL5416238 | 0.75 | HRH3 (1.00) | HRH3DRD2DRD3 | |
| SCHEMBL6292800 | 0.75 | HRH3 (1.00) | HRH3DRD2DRD3 | |
| SCHEMBL5261354 | 0.75 | HRH3 (1.00) | HRH3DRD2DRD3 | |
| SCHEMBL6633641 | 0.75 | HRH3 (1.00) | HRH3 | |
| SCHEMBL10674653 | 0.74 | HRH3 (0.67) | HRH3 | |
| SCHEMBL5260036 | 0.74 | HRH3 (1.00) | HRH3DRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6908929-B2 | Phenyl-substituted imidazopyridines | ORTHO-MCNEIL PHARMACEUTICAL, INC. (US) | 2005-06-21 | — | — | US | claimed |