Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.61 |
| ▸ | RIPK1 | Q13546 | 11/20 | 0.45 |
| ▸ | AURKA | O14965 | 1/20 | 0.45 |
| ▸ | PARP1 | P09874 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | SNCA | P37840 | 1/20 | 0.40 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.40 |
| ▸ | CDK1 | P06493 | 1/20 | 0.40 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.40 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.40 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28238848 | 0.85 | DAO (0.59) | DAORIPK1AURKAPARP1MAPT | |
| SCHEMBL10689563 | 0.85 | DAO (0.59) | DAORIPK1AURKAPARP1MAPT | |
| SCHEMBL3155901 | 0.79 | DAO (0.54) | DAORIPK1MAPTSNCACCNB2 | |
| SCHEMBL668758 | 0.76 | DAO (0.65) | DAORIPK1AURKAPARP1CCNB2 | |
| SCHEMBL435130 | 0.76 | DAO (0.65) | DAORIPK1AURKAPARP1CCNB2 | |
| SCHEMBL3714541 | 0.76 | DAO (1.00) | DAORIPK1AURKAPARP1 | |
| SCHEMBL1574005 | 0.76 | DAO (0.65) | DAORIPK1AURKAPARP1CCNB2 | |
| SCHEMBL21226786 | 0.76 | DAO (0.65) | DAORIPK1AURKAPARP1CCNB2 | |
| SCHEMBL15528142 | 0.76 | DAO (0.65) | DAORIPK1AURKAPARP1CCNB2 | |
| SCHEMBL29756947 | 0.76 | DAO (0.65) | DAORIPK1AURKAPARP1CCNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6875743-B1 | Cell adhesion inhibitors | BIOGEN, INC. (US) | 2005-04-05 | — | — | US | disclosed |