Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.62 |
| ▸ | DGKA | P23743 | 1/20 | 0.61 |
| ▸ | NAAA | Q02083 | 1/20 | 0.56 |
| ▸ | HTR2C | P28335 | 1/20 | 0.54 |
| ▸ | MGLL | Q99685 | 1/20 | 0.53 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.53 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.53 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | CNR1 | P21554 | 1/20 | 0.51 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.49 |
| ▸ | RAD52 | P43351 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | FAAH | O00519 | 2/20 | 0.48 |
| ▸ | PAM | P19021 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11445728 | 1.00 | TSHR (0.62) | TSHRDGKANAAAHTR2CMGLL | |
| SCHEMBL3117539 | 0.98 | TSHR (0.59) | TSHRDGKANAAAHTR2CMGLL | |
| SCHEMBL9615678 | 0.95 | TSHR (0.65) | TSHRDGKANAAAHTR2CMGLL | |
| SCHEMBL10457574 | 0.95 | TSHR (0.65) | TSHRDGKANAAAHTR2CMGLL | |
| SCHEMBL8661528 | 0.95 | TSHR (0.65) | TSHRDGKANAAAHTR2CMGLL | |
| SCHEMBL20869798 | 0.95 | TSHR (0.65) | TSHRDGKANAAAHTR2CMGLL | |
| SCHEMBL9852705 | 0.95 | TSHR (0.65) | TSHRDGKANAAAHTR2CMGLL | |
| SCHEMBL1856268 | 0.95 | TSHR (0.65) | TSHRDGKANAAAHTR2CMGLL | |
| SCHEMBL21983635 | 0.95 | TSHR (0.65) | TSHRDGKANAAAHTR2CMGLL | |
| SCHEMBL20500825 | 0.95 | TSHR (0.65) | TSHRDGKANAAAHTR2CMGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050250674-A1 | Nutritional and food supplement preparation comprising creatine and orotic acid complexes, derivatives and analogs | AMATO DANIEL | 2005-11-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050250674-A1 | Nutritional and food supplement preparation comprising creatine and orotic acid complexes, derivatives and analogs | CKMT1A; CKMT1B, OTC, OAT | TSHR 4185/4885DGKA 1274/4885NAAA 1262/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.