Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 14/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6420495 | 1.00 | HRH3 (0.48) | HRH3SLC6A4MAOBESR1ESR2 | |
| SCHEMBL225135 | 0.88 | ESR1 (0.49) | HRH3SLC6A4ESR1ESR2 | |
| SCHEMBL228108 | 0.88 | ESR1 (0.49) | HRH3SLC6A4ESR1ESR2 | |
| SCHEMBL4417105 | 0.86 | DRD2 (0.41) | — | |
| SCHEMBL227666 | 0.83 | DRD2 (0.41) | HRH3SLC6A4ESR1ESR2 | |
| SCHEMBL227766 | 0.80 | LTA4H (0.49) | HRH3MAOBESR1ESR2 | |
| SCHEMBL226814 | 0.80 | HRH3 (0.46) | HRH3SLC6A4MAOBESR1ESR2 | |
| SCHEMBL225012 | 0.80 | HRH3 (0.46) | HRH3SLC6A4MAOBESR1ESR2 | |
| SCHEMBL229972 | 0.80 | LTA4H (0.49) | HRH3MAOBESR1ESR2 | |
| SCHEMBL225651 | 0.80 | CYP26A1 (0.47) | ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1577288-B1 | Selective estrogen receptor modulators | EISAI R&D MAN CO LTD (JP) | 2014-07-23 | — | — | EP | disclosed |
| EP-1577288-A1 | SELECTIVE ESTROGEN RECEPTOR MODULATORS | Eisai Co., Ltd. (JP) | 2005-09-21 | — | — | EP | disclosed |