Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | PKM | P14618 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6420408 | 0.92 | LMNA (0.66) | LMNAALDH1A1PKMGAAHSD17B10 | |
| SCHEMBL2931120 | 0.85 | LMNA (0.58) | LMNAALDH1A1PKMGAAHSD17B10 | |
| SCHEMBL2905656 | 0.83 | LMNA (0.56) | LMNAALDH1A1PKMGAAHSD17B10 | |
| SCHEMBL6421089 | 0.81 | HSD17B10 (0.34) | LMNAALDH1A1HSD17B10MAPTKDM4E | |
| SCHEMBL9277493 | 0.78 | LMNA (0.71) | LMNAALDH1A1PKMGAAHSD17B10 | |
| SCHEMBL9515787 | 0.76 | LMNA (0.72) | LMNAALDH1A1PKMGAAHSD17B10 | |
| SCHEMBL19025301 | 0.76 | LMNA (0.68) | LMNAALDH1A1PKMGAAHSD17B10 | |
| SCHEMBL4434773 | 0.76 | LMNA (0.68) | LMNAALDH1A1PKMGAAHSD17B10 | |
| SCHEMBL4143905 | 0.75 | LMNA (0.71) | LMNAALDH1A1PKMGAAHSD17B10 | |
| Hydrochloric Acid SCHEMBL9096753 | 0.74 | LMNA (0.69) | LMNAALDH1A1PKMGAAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1047677-B1 | Process for the preparation of derivatives of 1,4,7,10-tetraazacyclododecane-1,4-diacetic acid | BRACCO SPA (IT) | 2005-07-20 | — | — | EP | claimed |