Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
| ▸ | CASP7 | P55210 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | CASP3 | P42574 | 1/20 | 0.31 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.31 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4933697 | 0.77 | ALDH1A1 (0.47) | CYP3A4MAPTALDH1A1HPGDHTT | |
| SCHEMBL7038026 | 0.77 | HPGD (0.41) | CYP3A4MAPTALDH1A1HPGDHTT | |
| SCHEMBL553110 | 0.73 | ALDH1A1 (0.49) | CYP3A4MAPTALDH1A1HPGDHTT | |
| SCHEMBL146503 | 0.71 | CYP1A2 (0.56) | CYP3A4MAPTALDH1A1HPGDHTT | |
| SCHEMBL605080 | 0.70 | ALDH1A1 (0.44) | CYP3A4MAPTALDH1A1HPGDHTT | |
| SCHEMBL29002800 | 0.68 | PTGER4 (0.50) | MAPTALDH1A1HPGDHTTKMT2A | |
| SCHEMBL20438859 | 0.67 | KDM4E (0.44) | MAPTALDH1A1HPGDHTTKMT2A | |
| SCHEMBL18487332 | 0.66 | DYRK1A (0.45) | MAPTALDH1A1HPGDHTTSMN1; SMN2 | |
| SCHEMBL10824846 | 0.66 | ALDH1A1 (0.56) | MAPTALDH1A1HPGDSMN1; SMN2LMNA | |
| SCHEMBL20434642 | 0.66 | MAPT (0.41) | MAPTALDH1A1HPGDHTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050119491-A1 | 2, 7-Substituted carbazoles and oligomers, polymers and co-polymers thereof | SHEFFIELD, THE UNIVERSITY OF (GB) | 2005-06-02 | — | — | US | disclosed |
| US-6833432-B2 | Electronics, optics | UNIVERSITE LAVAL (CA) | 2004-12-21 | — | — | US | disclosed |
| EP-1453802-A1 | 2, 7 - SUBSTITUTED CARBAZOLES AND OLIGOMERS, POLYMERS AND CO-POLYMERS THEREOF | THE UNIVERSITY OF SHEFFIELD (GB) | 2004-09-08 | — | — | EP | disclosed |
| WO-2003050086-A1 | 2, 7 - SUBSTITUTED CARBAZOLES AND OLIGOMERS, POLYMERS AND CO-POLYMERS THEREOF | THE UNIVERSITY OF SHEFFIELD (GB) | 2003-06-19 | — | — | WO | disclosed |
| US-20030092880-A1 | Conjugated poly(2,7-carbazole) derivatives and process for the preparation thereof | UNIVERSITE LAVAL (CA) | 2003-05-15 | — | — | US | disclosed |
| US-20020103332-A1 | Conjugated polycarbazole derivatives and process for the preparation thereof | UNIVERSITE LAVAL (CA) | 2002-08-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050119491-A1 | 2, 7-Substituted carbazoles and oligomers, polymers and co-polymers thereof | CBR3, OR10J3, ORC3 | CYP3A4 1219/4885CNR1 32/4885MAPT 3096/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.