Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Monoethanolamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethylenediamine SCHEMBL6422156 | 0.91 | CRHR1 (0.34) | CRHR1 | |
| SCHEMBL1634239 | 0.87 | CRHR1 (0.37) | CRHR1 | |
| SCHEMBL7244173 | 0.85 | CRHR1 (0.36) | CRHR1 | |
| SCHEMBL2907409 | 0.85 | CRHR1 (0.36) | CRHR1 | |
| SCHEMBL29528568 | 0.85 | CRHR1 (0.36) | CRHR1 | |
| SCHEMBL6422027 | 0.83 | CRHR1 (0.32) | CRHR1 | |
| SCHEMBL6422032 | 0.83 | CRHR1 (0.32) | CRHR1 | |
| Butylamine SCHEMBL6422969 | 0.82 | CRHR1 (0.33) | CRHR1 | |
| SCHEMBL8018204 | 0.75 | CRHR1 (0.49) | CRHR1 | |
| Monoethanolamine SCHEMBL2913256 | 0.74 | ALDH1A1 (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5173341-A | Coating wire with triazine-thiol derivative, drawing wire thorugh bath, polymerizing triazine-thiol | TOKYO ROPE MFG. CO., LTD. (JP) | 1992-12-22 | — | — | US | claimed |
| US-6905794-B2 | Air-hydrogen battery | HITACHI MAXELL, LTD. (JP) | 2005-06-14 | — | — | US | disclosed |
| US-20030143457-A1 | Air-hydrogen cell | HITACHI MAXELL ENERGY, LTD. (JP) | 2003-07-31 | — | — | US | disclosed |
| EP-0470280-B1 | Method for manufacturing polymeric coated steel wires for rubber reinforcement | TOKYO ROPE MFG CO (JP) | 1996-12-11 | — | — | EP | disclosed |
| US-5173341-A | Coating wire with triazine-thiol derivative, drawing wire thorugh bath, polymerizing triazine-thiol | TOKYO ROPE MFG. CO., LTD. (JP) | 1992-12-22 | — | — | US | disclosed |
| EP-0470280-A1 | Method for manufacturing polymeric coated steel wires for rubber reinforcement | TOKYO ROPE MANUFACTURING CO., LTD. (JP) | 1992-02-12 | — | — | EP | disclosed |