Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 7/20 | 1.00 |
| ▸ | CYP1A1 | P04798 | 6/20 | 1.00 |
| ▸ | CYP1A2 | P05177 | 6/20 | 1.00 |
| ▸ | CYP1B1 | Q16678 | 6/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 5/20 | 1.00 |
| ▸ | TP53 | P04637 | 3/20 | 1.00 |
| ▸ | CA12 | O43570 | 3/20 | 1.00 |
| ▸ | CA4 | P22748 | 3/20 | 1.00 |
| ▸ | CYP2C19 | P33261 | 3/20 | 1.00 |
| ▸ | CA7 | P43166 | 3/20 | 1.00 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 1.00 |
| ▸ | MAPT | P10636 | 3/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 1.00 |
| ▸ | XDH | P47989 | 2/20 | 1.00 |
| ▸ | HPGD | P15428 | 2/20 | 1.00 |
| ▸ | PKM | P14618 | 2/20 | 1.00 |
| ▸ | MAPK1 | P28482 | 2/20 | 1.00 |
| ▸ | CYP2C9 | P11712 | 2/20 | 1.00 |
| ▸ | DPP4 | P27487 | 2/20 | 1.00 |
| ▸ | GSK3B | P49841 | 2/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hesperetin SCHEMBL5202121 | 1.00 | CYP19A1 (1.00) | CYP19A1CYP1A1CYP1A2CYP1B1CYP3A4 | |
| Hesperetin SCHEMBL29534477 | 1.00 | CYP19A1 (1.00) | CYP19A1CYP1A1CYP1A2CYP1B1CYP3A4 | |
| Hesperetin SCHEMBL29359052 | 1.00 | CYP19A1 (1.00) | CYP19A1CYP1A1CYP1A2CYP1B1CYP3A4 | |
| Hesperetin SCHEMBL39833 | 1.00 | CYP19A1 (1.00) | CYP19A1CYP1A1CYP1A2CYP1B1CYP3A4 | |
| Hesperetin SCHEMBL765368 | 1.00 | CYP19A1 (1.00) | CYP19A1CYP1A1CYP1A2CYP1B1CYP3A4 | |
| Hesperetin SCHEMBL30696626 | 1.00 | CYP19A1 (1.00) | CYP19A1CYP1A1CYP1A2CYP1B1CYP3A4 | |
| Hesperetin SCHEMBL29484563 | 1.00 | CYP19A1 (1.00) | CYP19A1CYP1A1CYP1A2CYP1B1CYP3A4 | |
| Hesperetin SCHEMBL31689737 | 1.00 | CYP19A1 (1.00) | CYP19A1CYP1A1CYP1A2CYP1B1CYP3A4 | |
| Hesperetin SCHEMBL20929082 | 1.00 | CYP19A1 (1.00) | CYP19A1CYP1A1CYP1A2CYP1B1CYP3A4 | |
| Hesperetin SCHEMBL28595598 | 0.99 | CYP19A1 (0.98) | CYP19A1CYP1A1CYP1A2CYP1B1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108273070-B | Cell and drug targeting switching structure and preparation and application thereof | 上海交通大学 | 2020-10-16 | — | — | CN | claimed |
| CN-108273070-B | Cell and drug targeting switching structure and preparation and application thereof | 上海交通大学 | 2020-10-16 | — | — | CN | disclosed |
| EP-1514540-A1 | CALCIUM-CONTAINING TISSUE STRENGTHENING AGENTS AND USE THEREOF | Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo (JP) | 2005-03-16 | — | — | EP | disclosed |