Hesperetin

Hesperetin

SCHEMBL29359052

COc1ccc([C@@H]2CC(=O)c3c(O)cc(O)cc3O2)cc1O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 7/20 1.00
CYP1A1 P04798 6/20 1.00
CYP1A2 P05177 6/20 1.00
CYP1B1 Q16678 6/20 1.00
CYP3A4 P08684 5/20 1.00
TP53 P04637 3/20 1.00
CA12 O43570 3/20 1.00
CA4 P22748 3/20 1.00
CYP2C19 P33261 3/20 1.00
CA7 P43166 3/20 1.00
HSD17B10 Q99714 3/20 1.00
MAPT P10636 3/20 1.00
ALDH1A1 P00352 3/20 1.00
XDH P47989 2/20 1.00
HPGD P15428 2/20 1.00
PKM P14618 2/20 1.00
MAPK1 P28482 2/20 1.00
CYP2C9 P11712 2/20 1.00
DPP4 P27487 2/20 1.00
GSK3B P49841 2/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hesperetin SCHEMBL6422865 1.00 CYP19A1 (1.00) CYP19A1CYP1A1CYP1A2CYP1B1CYP3A4
Hesperetin SCHEMBL5202121 1.00 CYP19A1 (1.00) CYP19A1CYP1A1CYP1A2CYP1B1CYP3A4
Hesperetin SCHEMBL29534477 1.00 CYP19A1 (1.00) CYP19A1CYP1A1CYP1A2CYP1B1CYP3A4
Hesperetin SCHEMBL39833 1.00 CYP19A1 (1.00) CYP19A1CYP1A1CYP1A2CYP1B1CYP3A4
Hesperetin SCHEMBL765368 1.00 CYP19A1 (1.00) CYP19A1CYP1A1CYP1A2CYP1B1CYP3A4
Hesperetin SCHEMBL30696626 1.00 CYP19A1 (1.00) CYP19A1CYP1A1CYP1A2CYP1B1CYP3A4
Hesperetin SCHEMBL29484563 1.00 CYP19A1 (1.00) CYP19A1CYP1A1CYP1A2CYP1B1CYP3A4
Hesperetin SCHEMBL31689737 1.00 CYP19A1 (1.00) CYP19A1CYP1A1CYP1A2CYP1B1CYP3A4
Hesperetin SCHEMBL20929082 1.00 CYP19A1 (1.00) CYP19A1CYP1A1CYP1A2CYP1B1CYP3A4
Hesperetin SCHEMBL28595598 0.99 CYP19A1 (0.98) CYP19A1CYP1A1CYP1A2CYP1B1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 171 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025217418-A1 SAMPLE PREPARATION FOR NUCLEIC ACIDS Life Technologies Corporation (US) 2025-10-16 WO claimed
WO-2025034736-A1 SAMPLE PREPARATION FOR NUCLEIC ACIDS Life Technologies Corporation (US) 2025-02-13 WO claimed
CN-118996720-A Medical elastic thread easy to shear and low in divergence 微尔创(武汉)医疗科技有限公司 2024-11-22 CN claimed
US-20230090146-A1 MICROEMULSIONS AND USES THEREOF TO DISPLACE OIL IN HETEROGENEOUS POROUS MEDIA UNIVERSITY OF WYOMING 2023-03-23 US claimed
WO-2022018376-A2 ECOBIOLOGICAL FORMULATION, COMPATIBLE WITH CELL LIFE, USABLE IN THE COSMETIC, DERMOPHARMACEUTICAL OR VETERINARY FIELDS NAOS INSTITUTE OF LIFE SCIENCE (FR) 2022-01-27 WO claimed
US-12637560-B2 Resin composition DUPONT ELECTRONIC MATERIALS INTERNATIONAL, LLC (US) 2026-05-26 US disclosed
EP-4729046-A2 COMPOSITIONS HAVING ENHANCED DEPOSITION OF SURFACTANT SOLUBLE ANTIDANDRUFF AGENTS The Procter & Gamble Company (US) 2026-04-22 EP disclosed
EP-3784352-B1 COMPOSITIONS HAVING ENHANCED DEPOSITION OF SURFACTANT SOLUBLE ANTIDANDRUFF AGENTS PROCTER & GAMBLE (US) 2026-03-11 EP disclosed
US-12557843-B2 Other than cannabinoids, flavonoids, and terpenes LARSON RAYMOND LOUIS (US) 2026-02-24 US disclosed
US-20260048108-A1 CANCER THERAPY COMPOSITIONS AND USES THEREOF HDT BIO CORP (US) 2026-02-19 US disclosed
US-20260041754-A1 NANOPARTICLE COMPLEXES FOR ENHANCED SAFETY HDT BIO CORP (US) 2026-02-12 US disclosed
US-12485163-B2 Cancer therapy compositions and uses thereof HDT BIO CORP. (US) 2025-12-02 US disclosed
US-20220112321-A1 HIGH REFRACTIVE INDEX MATERIALS U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT 2022-04-14 US disclosed
EP-3981806-A1 HIGH REFRACTIVE INDEX MATERIALS Rohm and Haas Electronic Materials LLC (US) 2022-04-13 EP disclosed
CN-114316137-A High refractive index materials 罗门哈斯电子材料有限责任公司 2022-04-12 CN disclosed
US-11291616-B2 Delivery of surfactant soluble anti-dandruff agent THE PROCTER AND GAMBLE COMPANY (US) 2022-04-05 US disclosed
CN-107530257-B Delivery of surfactant soluble antidandruff agents 宝洁公司 2022-03-29 CN disclosed
EP-3532013-B1 HAIR COMPOSITIONS WITH INCREASED DEPOSITION OF ACTIVE AGENTS PROCTER & GAMBLE (US) 2022-03-16 EP disclosed
CN-114072163-A New material for healing skin wound and preventing scar 芝加哥大学 2022-02-18 CN disclosed
WO-2022018376-A2 ECOBIOLOGICAL FORMULATION, COMPATIBLE WITH CELL LIFE, USABLE IN THE COSMETIC, DERMOPHARMACEUTICAL OR VETERINARY FIELDS NAOS INSTITUTE OF LIFE SCIENCE (FR) 2022-01-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11291616-B2 Delivery of surfactant soluble anti-dandruff agent SMURF1, SMURF2, POLR1C CYP19A1 1706/4885CYP1A1 2991/4885CYP1A2 3418/4885
US-12637560-B2 Resin composition TAF1, TAF11, TAF5 CYP19A1 2571/4885CYP1A1 2337/4885CYP1A2 3802/4885
US-20260048108-A1 CANCER THERAPY COMPOSITIONS AND USES THEREOF SLC11A2, CD47, PDCD1LG2 CYP19A1 4389/4885CYP1A1 4860/4885CYP1A2 4838/4885
US-20260041754-A1 NANOPARTICLE COMPLEXES FOR ENHANCED SAFETY ITGAL, ITGA2B, ITGA2 CYP19A1 3714/4885CYP1A1 2657/4885CYP1A2 3698/4885
US-12557843-B2 Other than cannabinoids, flavonoids, and terpenes CCT5, CNR2, CPNE4 CYP19A1 2327/4885CYP1A1 932/4885CYP1A2 884/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.