SCHEMBL6422916

SCHEMBL6422916

CCCCCCCCCCCC[Si](C)(C)c1cccs1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KCNH2 Q12809 1/20 0.39
HDAC1 Q13547 1/20 0.38
HDAC11 Q96DB2 1/20 0.38
HDAC8 Q9BY41 1/20 0.38
HDAC6 Q9UBN7 1/20 0.38
ALDH1A1 P00352 3/20 0.37
KDM4E B2RXH2 1/20 0.37
GAA P10253 1/20 0.37
TSHR P16473 2/20 0.35
MAPT P10636 4/20 0.34
CNR1 P21554 3/20 0.34
CNR2 P34972 3/20 0.34
HTT P42858 2/20 0.34
L3MBTL1 Q9Y468 2/20 0.34
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
GAPDH P04406 1/20 0.34
POLB P06746 1/20 0.34
ALOX15 P16050 1/20 0.34
NR4A1 P22736 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19600567 0.80 TAAR1 (0.47) TSHRL3MBTL1POLBTAAR1
SCHEMBL19600571 0.76 KDM4E (0.33) ALDH1A1KDM4EGAATSHRMAPT
SCHEMBL6944627 0.71 GSK3B (0.35) ALDH1A1KDM4ETSHRMAPTL3MBTL1
Heptane SCHEMBL8571539 0.70 KDM4E (0.50) HDAC1HDAC11HDAC8HDAC6ALDH1A1
SCHEMBL271561 0.69 TAAR1 (0.57) KCNH2HDAC1HDAC11HDAC8HDAC6
SCHEMBL272288 0.69 TAAR1 (0.57) KCNH2HDAC1HDAC11HDAC8HDAC6
SCHEMBL2734280 0.69 TAAR1 (0.57) KCNH2HDAC1HDAC11HDAC8HDAC6
SCHEMBL270626 0.69 TAAR1 (0.57) KCNH2HDAC1HDAC11HDAC8HDAC6
SCHEMBL20482223 0.69 NR1H2 (0.46) KCNH2ALDH1A1CNR1CNR2HTT
SCHEMBL271466 0.69 TAAR1 (0.57) KCNH2HDAC1HDAC11HDAC8HDAC6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6885038-B2 Light-emitting polymers and polymer light-emitting diodes AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2005-04-26 US disclosed
US-20030088043-A1 Light-emitting polymers and polymer light-emitting diodes AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2003-05-08 US disclosed