SCHEMBL19600567

SCHEMBL19600567

C[Si](C)(CCCN)c1cccs1

nearest known ligand 0.47

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 1/20 0.47
MAOB P27338 1/20 0.39
SLC6A2 P23975 1/20 0.35
LTA4H P09960 2/20 0.33
TSHR P16473 1/20 0.33
POLB P06746 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.31
USP2 O75604 1/20 0.31
ADRA2A P08913 1/20 0.31
ADRA2B P18089 1/20 0.31
ADRA2C P18825 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6422916 0.80 KCNH2 (0.39) TAAR1TSHRPOLBL3MBTL1
SCHEMBL19600571 0.77 KDM4E (0.33) TAAR1MAOBTSHRPOLBUSP2
SCHEMBL6944627 0.72 GSK3B (0.35) TAAR1TSHRL3MBTL1ADRA2AADRA2B
SCHEMBL6003572 0.70 MAOA (0.37) TAAR1
SCHEMBL486510 0.69 NR1H2 (0.43)
SCHEMBL3865502 0.68 MGAM (0.40) TAAR1
SCHEMBL20550992 0.68 FBP1 (0.36) TAAR1TSHRL3MBTL1
SCHEMBL2290788 0.68 FBP1 (0.36) TAAR1TSHRL3MBTL1
SCHEMBL2341397 0.68
SCHEMBL7739043 0.68 NR1H2 (0.37) TAAR1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190304707-A1 PHOTOELECTRIC CONVERSION ELEMENT, SOLAR CELL AND COMPOSITION FUJIFILM CORPORATION (JP) 2019-10-03 US disclosed
US-10418186-B2 Photoelectric conversion element, solar cell and composition FUJIFILM CORPORATION (JP) 2019-09-17 US disclosed
US-20170330694-A1 PHOTOELECTRIC CONVERSION ELEMENT, SOLAR CELL AND COMPOSITION FUJIFILM CORPORATION (JP) 2017-11-16 US disclosed
US-20170330694-A1 PHOTOELECTRIC CONVERSION ELEMENT, SOLAR CELL AND COMPOSITION FUJIFILM CORPORATION (JP) 2017-11-16 US disclosed