Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.31 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.30 |
| ▸ | MEN1 | O00255 | 2/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | DPP4 | P27487 | 1/20 | 0.30 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.30 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8983864 | 0.75 | — | — | |
| SCHEMBL20550992 | 0.74 | FBP1 (0.36) | TAAR1HSD17B10TSHRL3MBTL1KDM4E | |
| SCHEMBL2341397 | 0.74 | — | — | |
| SCHEMBL2290788 | 0.74 | FBP1 (0.36) | TAAR1HSD17B10TSHRL3MBTL1KDM4E | |
| SCHEMBL7739043 | 0.74 | NR1H2 (0.37) | TAAR1HSD17B10TSHRKDM4EMEN1 | |
| SCHEMBL19600567 | 0.72 | TAAR1 (0.47) | TAAR1TSHRL3MBTL1ADRA2AADRA2B | |
| SCHEMBL6422916 | 0.71 | KCNH2 (0.39) | TAAR1HSD17B10TSHRL3MBTL1KDM4E | |
| SCHEMBL10534909 | 0.70 | KIF11 (0.32) | L3MBTL1KDM4ETDP1MEN1KMT2A | |
| SCHEMBL10534914 | 0.70 | KIF11 (0.32) | L3MBTL1KDM4ETDP1MEN1KMT2A | |
| SCHEMBL9190818 | 0.70 | ALDH1A1 (0.33) | TAAR1HSD17B10TSHRL3MBTL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0998477-B1 | Alkyl-4-silylheterocyclic phenols and thiophenols as antioxidant agents | AVENTIS PHARMA INC (US) | 2003-03-26 | — | — | EP | disclosed |
| US-6121463-A | ADMINISTERING AS ANTI-ATHEROSCLEROTIC AGENTS | HOECHST MARION ROUSSEL, INC. (US) | 2000-09-19 | — | — | US | disclosed |
| EP-0303802-A1 | Thienyl-azolylmethyl-silanes | AGROLINZ AGRARCHEMIKALIEN GESELLSCHAFT M.B.H. (AT) | 1989-02-22 | — | — | EP | disclosed |
| WO-1989000573-A1 | NEW THIENYL AZOLYLMETHYL SILANES | AGROLINZ AGRARCHEMIKALIEN GESELLSCHAFT M.B.H. (AT) | 1989-01-26 | — | — | WO | disclosed |