SCHEMBL6422982

SCHEMBL6422982

Nc1ccc(C(O)c2ccc(N)c(O)c2)cc1O

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 4/20 0.52
HSD17B10 Q99714 3/20 0.52
CYP3A4 P08684 2/20 0.52
MAPT P10636 6/20 0.46
KDM4E B2RXH2 6/20 0.46
KMT2A Q03164 3/20 0.46
GAA P10253 3/20 0.46
MEN1 O00255 2/20 0.46
POLB P06746 2/20 0.46
RAB9A P51151 1/20 0.46
HIF1A Q16665 2/20 0.43
ALDH1A1 P00352 2/20 0.43
ALOX12 P18054 1/20 0.43
HTT P42858 1/20 0.43
TDP1 Q9NUW8 7/20 0.42
RECQL P46063 6/20 0.42
BLM P54132 4/20 0.42
LMNA P02545 4/20 0.42
APEX1 P27695 3/20 0.42
HPGD P15428 3/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21368916 0.84 ALDH1A1 (0.47) ALOX15HSD17B10CYP3A4MAPTKDM4E
SCHEMBL11530733 0.80 TDP1 (0.43) ALOX15HSD17B10CYP3A4MAPTKDM4E
SCHEMBL5673396 0.79 GAA (0.52) ALOX15HSD17B10CYP3A4MAPTKDM4E
SCHEMBL5595265 0.79 GAA (0.69) ALOX15HSD17B10CYP3A4MAPTKDM4E
SCHEMBL30659005 0.79 GAA (0.69) ALOX15HSD17B10CYP3A4MAPTKDM4E
SCHEMBL27533485 0.79 ALOX15 (0.50) ALOX15HSD17B10CYP3A4MAPTKDM4E
SCHEMBL27600847 0.77 ALOX15 (0.48) ALOX15HSD17B10CYP3A4MAPTKDM4E
SCHEMBL23005780 0.76 ESR1 (0.50) ALOX15HSD17B10CYP3A4MAPTKDM4E
SCHEMBL18382552 0.76 ALOX15 (0.46) ALOX15HSD17B10CYP3A4MAPTKDM4E
SCHEMBL29897184 0.76 ALOX15 (0.46) ALOX15HSD17B10CYP3A4MAPTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021065540-A1 PHOTOSENSITIVE RESIN COMPOSITION, DRY FILM, CURED OBJECT, AND ELECTRONIC COMPONENT 太陽ホールディングス株式会社 2021-04-08 WO disclosed
US-6955712-B2 Proton-conducting polymer with acid groups in side chains, preparation method thereof, polymer membrane manufactured using the polymer, and fuel cell using the polymer membrane SAMSUNG SDI CO., LTD. (KR) 2005-10-18 US disclosed
US-20040097695-A1 Proton-conducting polymer with acid groups in side chains, preparation method thereof, polymer membrane manufactured using the polymer, and fuel cell using the polymer membrane SAMSUNG SDI CO., LTD. (KR) 2004-05-20 US disclosed