Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | LTB4R | Q15722 | 2/20 | 0.43 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.43 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.42 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.42 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.42 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.42 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.42 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.42 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | GPR17 | Q13304 | 1/20 | 0.40 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.40 |
| ▸ | CTSA | P10619 | 1/20 | 0.40 |
| ▸ | MME | P08473 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8473000 | 0.83 | ALDH1A1 (0.51) | ALDH1A1PTGER1FFAR1LMNAHTT | |
| SCHEMBL5507623 | 0.79 | ALDH1A1 (0.53) | ALDH1A1FFAR1CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL22714458 | 0.74 | ALDH1A1 (0.53) | ALDH1A1FFAR1 | |
| SCHEMBL3992606 | 0.74 | BCL2 (0.48) | PTGS2 | |
| SCHEMBL26133929 | 0.74 | FFAR1 (0.59) | PTGER1PTGER4PTGER3PTGER2FFAR1 | |
| SCHEMBL4027432 | 0.74 | ALDH1A1 (0.67) | ALDH1A1PTGER1FFAR1LMNAFFAR4 | |
| SCHEMBL2776945 | 0.73 | MAPT (0.53) | ALDH1A1PTGER1FFAR1HTTMAPT | |
| SCHEMBL11605014 | 0.73 | ALDH1A1 (0.51) | ALDH1A1MAPTTHRB | |
| SCHEMBL4408369 | 0.73 | ALDH1A1 (0.51) | ALDH1A1PTGER2 | |
| SCHEMBL5447638 | 0.73 | ALDH1A1 (0.51) | ALDH1A1FFAR1LMNAHTTFFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0960096-B1 | SUBSTITUTED BETA-THIOCARBOXYLIC ACIDS | AVENTIS PHARMA INC (US) | 2005-04-06 | — | — | EP | claimed |
| US-6306873-B1 | Substituted β-thiocarboxylic acids | AVENTIS PHARMACEUTICALS PRODUCTS INC. | 2001-10-23 | — | — | US | claimed |
| EP-0960096-B1 | SUBSTITUTED BETA-THIOCARBOXYLIC ACIDS | AVENTIS PHARMA INC (US) | 2005-04-06 | — | — | EP | disclosed |