Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NSD2 | O96028 | 1/20 | 0.40 |
| ▸ | CASP6 | P55212 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | PNP | P00491 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | PARP1 | P09874 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5612938 | 0.76 | NSD2 (0.39) | NSD2CASP6ALDH1A1L3MBTL1LMNA | |
| SCHEMBL4239753 | 0.76 | PNP (0.34) | ALDH1A1LMNAKDM4EGLAPMP22 | |
| SCHEMBL20564 | 0.76 | ADORA3 (0.38) | ALDH1A1L3MBTL1KDM4EMAPTPARP1 | |
| SCHEMBL29819457 | 0.76 | KDM4E (0.51) | NSD2CASP6ALDH1A1LMNAKDM4E | |
| SCHEMBL3916442 | 0.73 | ADORA1 (0.30) | — | |
| SCHEMBL12726686 | 0.73 | CSNK2A2 (0.33) | ALDH1A1LMNAKDM4EMAPTGAA | |
| SCHEMBL13522498 | 0.73 | ADORA1 (0.30) | — | |
| SCHEMBL10121590 | 0.70 | ADORA3 (0.32) | — | |
| SCHEMBL5489090 | 0.69 | NSD2 (0.36) | NSD2CASP6ALDH1A1L3MBTL1KDM4E | |
| SCHEMBL15695429 | 0.67 | PIK3CA (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1112281-B1 | PTERIDINE NUCLEOTIDE ANALOGS | US GOV HEALTH & HUMAN SERV (US) | 2005-11-23 | — | — | EP | disclosed |
| US-6716971-B1 | CAN BE USED IN THE CHEMICAL SYNTHESIS OF FLUORESCENT OLIGONUCLEOTIDE. | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES | 2004-04-06 | — | — | US | disclosed |
| EP-1112281-A1 | PTERIDINE NUCLEOTIDE ANALOGS | THE GOVERNMENT OF THE UNITED STATES OF AMERICA as represented by the Secretary of the Department of Health and Human Services (US) | 2001-07-04 | — | — | EP | disclosed |
| WO-2000014101-A1 | PTERIDINE NUCLEOTIDE ANALOGS | THE GOVERNMENT OF THE UNITED STATES OF AMERICA REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2000-03-16 | — | — | WO | disclosed |