SCHEMBL20564

SCHEMBL20564

Cc1nc(N)c2nc(C)[nH]c2n1

nearest known ligand 0.47

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ADORA3 P0DMS8 2/20 0.38
CSNK2A1 P68400 2/20 0.33
PARP1 P09874 1/20 0.33
ALDH1A1 P00352 2/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
ADORA1 P30542 4/20 0.32
ADORA2A P29274 3/20 0.32
ADORA2B P29275 1/20 0.31
KDM4E B2RXH2 1/20 0.31
GAA P10253 1/20 0.31
MAPT P10636 1/20 0.31
PKM P14618 1/20 0.31
KMT2A Q03164 1/20 0.31
NPY5R Q15761 1/20 0.31
DYRK1A Q13627 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2953678 0.83 ADORA3 (0.38) ADORA3CSNK2A1PARP1ALDH1A1L3MBTL1
SCHEMBL4239753 0.83 PNP (0.34) ADORA3CSNK2A1ALDH1A1ADORA1ADORA2A
SCHEMBL10121590 0.80 ADORA3 (0.32) ADORA3ADORA1ADORA2A
SCHEMBL3916442 0.79 ADORA1 (0.30) ADORA3ADORA1ADORA2A
SCHEMBL12592352 0.79 ADORA3 (0.35) ADORA3CSNK2A1PARP1ALDH1A1L3MBTL1
SCHEMBL19633362 0.79 CDK1 (0.37) ADORA3CSNK2A1PARP1ALDH1A1L3MBTL1
SCHEMBL12726686 0.79 CSNK2A2 (0.33) ADORA3CSNK2A1ALDH1A1ADORA1ADORA2A
SCHEMBL13522498 0.79 ADORA1 (0.30) ADORA3ADORA1ADORA2A
SCHEMBL9797840 0.77 ADORA3 (0.41) ADORA3CSNK2A1ALDH1A1L3MBTL1ADORA1
SCHEMBL6423600 0.76 NSD2 (0.40) PARP1ALDH1A1L3MBTL1KDM4EGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1269 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4705481-A2 CIRCULAR RNA COMPOSITIONS AND METHODS Orna Therapeutics, Inc. (US) 2026-03-11 EP claimed
US-20250129308-A1 SEMICONDUCTOR TREATMENT LIQUID, TREATMENT METHOD FOR OBJECT TO BE TREATED, AND MANUFACTURING METHOD OF ELECTRONIC DEVICE FUJIFILM CORP (JP) 2025-04-24 US claimed
WO-2024233308-A2 CIRCULAR RNA COMPOSITIONS AND METHODS ORNA THERAPEUTICS, INC. (US) 2024-11-14 WO claimed
WO-2024014224-A1 SEMICONDUCTOR PROCESSING LIQUID, METHOD FOR PROCESSING OBJECT TO BE PROCESSED, AND METHOD FOR MANUFACTURING ELECTRONIC DEVICE 富士フイルム株式会社 2024-01-18 WO claimed
CN-111741967-A Nucleoside analogue, preparation method and application 深圳市真迈生物科技有限公司 2020-10-02 CN claimed
US-9725474-B2 Modified nucleic acid TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2017-08-08 US claimed
CN-106967068-A N6The photochemistry demethyl method of methyl adenine 中国科学院化学研究所 2017-07-21 CN claimed
WO-2016126987-A1 COMPOSITIONS AND METHODS FOR SYNTHETIC GENE ASSEMBLY Twist Bioscience Corporation (US) 2016-08-11 WO claimed
US-9284343-B2 2′-O-aminooxymethyl nucleoside derivatives for use in the synthesis and modification of nucleosides, nucleotides and oligonucleotides THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2016-03-15 US claimed
EP-2694524-A1 2'-O-AMINOOXYMETHYL NUCLEOSIDE DERIVATIVES FOR USE IN THE SYNTHESIS AND MODIFICATION OF NUCLEOSIDES, NUCLEOTIDES AND OLIGONUCLEOTIDES The U.S.A. As Represented By The Secretary, Department Of Health And Human Services (US) 2014-02-12 EP claimed
WO-2013071079-A1 LIN28/LET-7 CRYSTAL STRUCTURES, PURIFICATION PROTOCOLS, AND MOLECULAR PROBES SUITABLE FOR SCREENING ASSAYS AND THERAPEUTICS PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2013-05-16 WO claimed
EP-2547769-A1 MINOR GROOVE BINDER (MGB)-OLIGONUCLEOTIDE MIRNA ANTAGONISTS Elitech Holding B.V. (NL) 2013-01-23 EP claimed
WO-2012138530-A1 2'-O-AMINOOXYMETHYL NUCLEOSIDE DERIVATIVES FOR USE IN THE SYNTHESIS AND MODIFICATION OF NUCLEOSIDES, NUCLEOTIDES AND OLIGONUCLEOTIDES THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2012-10-11 WO claimed
WO-2011066312-A1 MINOR GROOVE BINDER (MGB)-OLIGONUCLEOTIDE MIRNA ANTAGONISTS ELITECH HOLDING B.V. (NL) 2011-06-03 WO claimed
US-20050239727-A1 for use in cosmetics, drugs SILDEHA SWISS SA (CH) 2005-10-27 US claimed
EP-1525224-A1 HYALURONIC ACID DERIVATIVES Jasper Ltd. Liability Co. (US) 2005-04-27 EP claimed
WO-2004013182-A1 HYALURONIC ACID DERIVATIVES JASPER LTD LIABILITY CO. (US) 2004-02-12 WO claimed
WO-2026106956-A1 DISULFIDE-STABILIZED NOROVIRUS VIRUS-LIKE PARTICLE DESIGN MERCK SHARP & DOHME LLC (US) 2026-05-21 WO disclosed
US-4543388-A Thermosettable polymers or prepolymers prepared from polymethylated pyrazines and aromatic polyaldehydes and cured products therefrom THE DOW CHEMICAL COMPANY (US) 1985-09-24 US disclosed
EP-0147689-A2 A method of inducing antitumor immunocytes, and a process for producing antitumor immunocytes and antitumor immunocytes produced by the process Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1985-07-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050239727-A1 for use in cosmetics, drugs HINT1, NUDT1, NNT ADORA3 26/4885CSNK2A1 4747/4885PARP1 215/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.