Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSPA5 | P11021 | 2/20 | 0.44 |
| ▸ | DHFR | P00374 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | GAA | P10253 | 4/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | GSR | P00390 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | BLM | P54132 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | GMNN | O75496 | 1/20 | 0.39 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6424337 | 0.93 | HSPA5 (0.47) | HSPA5DHFRALDH1A1GAATSHR | |
| SCHEMBL13809316 | 0.91 | HSPA5 (0.37) | HSPA5DHFRALDH1A1GAATSHR | |
| SCHEMBL6423186 | 0.87 | HSPA5 (0.53) | HSPA5DHFRALDH1A1GAATSHR | |
| SCHEMBL15866583 | 0.86 | HSPA5 (0.52) | HSPA5DHFRALDH1A1GAATSHR | |
| SCHEMBL13809505 | 0.82 | HSPA5 (0.39) | HSPA5DHFRALDH1A1GAATSHR | |
| SCHEMBL13809317 | 0.82 | HSPA5 (0.39) | HSPA5DHFRALDH1A1GAATSHR | |
| SCHEMBL6423780 | 0.82 | HSPA5 (0.39) | HSPA5DHFRALDH1A1GAATSHR | |
| SCHEMBL13283989 | 0.82 | HSPA5 (0.33) | HSPA5DHFRCA1CA2 | |
| SCHEMBL13283990 | 0.81 | HSPA5 (0.38) | HSPA5DHFRALDH1A1GAATSHR | |
| SCHEMBL15866569 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2079677-B1 | MACROMOLECULAR AMINE-PHENOLIC ANTIOXIDANT COMPOSITIONS, PROCESS TECHNOLOGY THEREOF, AND USES THEREOF | ALBEMARLE CORP (US) | 2014-07-09 | — | — | EP | disclosed |
| US-8455414-B2 | Macromolecular amine-phenolic antioxidant compositions, process technology thereof, and uses thereof | ALBEMARLE CORPORATION (US) | 2013-06-04 | — | — | US | disclosed |
| US-20120115764-A1 | MACROMOLECULAR AMINE-PHENOLIC ANTIOXIDANT COMPOSITIONS, PROCESS TECHNOLOGY THEREOF, AND USES THEREOF | ALBEMARLE CORPORATION (US) | 2012-05-10 | — | — | US | disclosed |
| WO-2009073378-A1 | INDUSTRIAL OIL FORMULATIONS CONTAINING MACROMOLECULAR ANTIOXIDANTS | ALBEMARLE CORPORATION (US) | 2009-06-11 | — | — | WO | disclosed |
| WO-2008048989-A2 | MACROMOLECULAR AMINE-PHENOLIC ANTIOXIDANT COMPOSITIONS, PROCESS TECHNOLOGY THEREOF, AND USES THEREOF | ALBEMARLE CORPORATION (US) | 2008-04-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120115764-A1 | MACROMOLECULAR AMINE-PHENOLIC ANTIOXIDANT COMPOSITIONS, PROCESS TECHNOLOGY THEREOF, AND USES THEREOF | PNMT, COMT, MAOA | HSPA5 1734/4885DHFR 3344/4885ALDH1A1 957/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.