SCHEMBL8002486

SCHEMBL8002486

CC1(C)CCC[Si](C)(CCCOCC2CO2)O1

nearest known ligand 0.46

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.46
SMN1; SMN2 Q16637 1/20 0.45
ALDH1A1 P00352 2/20 0.43
TDP1 Q9NUW8 1/20 0.43
MAPK1 P28482 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9760116 0.80 TSHR (0.45) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL23064995 0.77 TSHR (0.42) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL642391 0.77 TSHR (0.53) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL8002490 0.74 TSHR (0.45) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL17669147 0.71 SMN1; SMN2 (0.47) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL16100946 0.71 SMN1; SMN2 (0.47) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL2006386 0.71 TSHR (0.61) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL2066081 0.71 TSHR (0.61) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL13532301 0.71 TSHR (0.61) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL16661604 0.71 TSHR (0.61) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110028763-B Preparation method of low-density high-rate epoxy resin microporous material 西北工业大学 2021-08-06 CN claimed
CN-110028763-B Preparation method of low-density high-rate epoxy resin microporous material 西北工业大学 2021-08-06 CN disclosed
US-6013718-A ORGANOSILANE BONDING AGENT COUPLES SILICA FILLER TO THE DIENE POLYMER BEARING A SINGLE SILANOL FUNCTIONAL GROUP OR POLYSILOXANE BLOCK HAVING A SINGLE SILANOL END; REDUCED HYSTERESIS, USE AS A TIRE TREAD MICHELIN & CIE (FR) 2000-01-11 US disclosed