Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8307825 | 0.89 | L3MBTL1 (0.39) | TACR1 | |
| SCHEMBL6592845 | 0.85 | TACR2 (0.44) | TACR2TACR1 | |
| SCHEMBL6595201 | 0.82 | TACR2 (0.50) | TACR2TACR1 | |
| SCHEMBL8452957 | 0.80 | TACR2 (0.37) | TACR2 | |
| SCHEMBL6595186 | 0.78 | TACR2 (0.47) | TACR2TACR1 | |
| SCHEMBL6425195 | 0.77 | TACR2 (0.45) | TACR2TACR1 | |
| SCHEMBL6425190 | 0.77 | TACR2 (0.45) | TACR2TACR1 | |
| SCHEMBL6424008 | 0.76 | TACR2 (0.44) | TACR2TACR1 | |
| SCHEMBL6424010 | 0.76 | TACR2 (0.44) | TACR2TACR1 | |
| SCHEMBL6595659 | 0.76 | TP53 (0.39) | TACR2TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0888338-A1 | NOVEL SUBSTITUTED N-METHYL-N-(4-(4-(1H-BENZIMIDAZOL-2-YL) 1,4]DIAZEPAN-1-YL)-2-(ARYL)BUTYL)BENZAMIDES USEFUL FOR THE TREATMENT OF ALLERGIC DISEASES | HOECHST MARION ROUSSEL, INC. (US) | 1999-01-07 | — | — | EP | disclosed |
| WO-1997030991-A1 | NOVEL SUBSTITUTED N-METHYL-N-(4-(4-(1H-BENZIMIDAZOL-2-YL)[1,4]DIAZEPAN-1-YL)-2-(ARYL)BUTYL)BENZAMIDES USEFUL FOR THE TREATMENT OF ALLERGIC DISEASES | HOECHST MARION ROUSSEL, INC. (US) | 1997-08-28 | — | — | WO | disclosed |