SCHEMBL6424052

SCHEMBL6424052

C=CC(=O)Oc1ccc(CC(C)c2ccc(OC(=O)C=C)c(OCC)c2OCC)c(OCC)c1OCC

nearest known ligand 0.38

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
THRB P10828 3/20 0.38
THRA P10827 1/20 0.38
ACACB O00763 2/20 0.34
EGFR P00533 1/20 0.31
ALDH1A1 P00352 1/20 0.31
TYMS P04818 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL534176 0.84 ALDH1A1 (0.31) ACACBALDH1A1
SCHEMBL29817538 0.84 ALDH1A1 (0.31) ACACBALDH1A1
SCHEMBL331318 0.83 THRB (0.44) THRBTHRAEGFRALDH1A1TYMS
SCHEMBL30029361 0.83 THRB (0.44) THRBTHRAEGFRALDH1A1TYMS
SCHEMBL1322766 0.81 THRB (0.49) THRBTHRAEGFRALDH1A1TYMS
SCHEMBL5178022 0.81 THRB (0.39) THRBTHRAACACBEGFRALDH1A1
SCHEMBL28298722 0.80 THRB (0.33) THRBTHRAACACB
SCHEMBL28119567 0.80 THRB (0.45) THRBTHRAEGFRALDH1A1TYMS
SCHEMBL2154420 0.76 THRB (0.42) THRBTHRAEGFRALDH1A1TYMS
SCHEMBL27645818 0.75 THRB (0.41) THRBTHRAEGFRALDH1A1TYMS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1266686-B1 HYDROPHOBIC SUBSTANCE ADSORBENTS SEKISUI CHEMICAL CO LTD (JP) 2005-04-27 EP disclosed
US-20030176609-A1 Hydrophobic substance adsorbents SEKISUI CHEMICAL CO. LTD. (JP) 2003-09-18 US disclosed
EP-1266686-A1 HYDROPHOBIC SUBSTANCE ADSORBENTS SEKISUI CHEMICAL CO., LTD. (JP) 2002-12-18 EP disclosed