Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Dichloroacetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.91 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.38 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.38 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dichloroacetic Acid SCHEMBL6424092 | 1.00 | — | — | |
| Dichloroacetic Acid SCHEMBL3612723 | 1.00 | — | — | |
| Dichloroacetic Acid SCHEMBL7777 | 0.95 | — | — | |
| Dichloroacetic Acid SCHEMBL5307050 | 0.95 | LMNA (1.00) | LMNAALDH1A1TSHRTHRBRECQL | |
| Dichloroacetic Acid SCHEMBL1331776 | 0.95 | — | — | |
| Dichloroacetic Acid SCHEMBL23923240 | 0.91 | — | — | |
| Dichloroacetic Acid SCHEMBL7263077 | 0.91 | — | — | |
| Dichloroacetic Acid SCHEMBL6913523 | 0.91 | — | — | |
| Dichloroacetic Acid SCHEMBL8610684 | 0.91 | — | — | |
| Dichloroacetic Acid SCHEMBL20876907 | 0.91 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005071306-A1 | CONTAINER WITH TRANSPARENT LINER AND SEMITRANSPARENT WALL | KOLDYBAEV SERGEI GLEBOVICH (CZ) | 2005-08-04 | — | — | WO | claimed |
| WO-2005071306-A1 | CONTAINER WITH TRANSPARENT LINER AND SEMITRANSPARENT WALL | KOLDYBAEV SERGEI GLEBOVICH (CZ) | 2005-08-04 | — | — | WO | disclosed |