Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.71 |
| ▸ | MAPT | P10636 | 8/20 | 0.71 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.71 |
| ▸ | RXRA | P19793 | 5/20 | 0.71 |
| ▸ | RARA | P10276 | 4/20 | 0.71 |
| ▸ | RARB | P10826 | 4/20 | 0.71 |
| ▸ | RARG | P13631 | 4/20 | 0.71 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.71 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.71 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.71 |
| ▸ | APP | P05067 | 4/20 | 0.71 |
| ▸ | SNCA | P37840 | 4/20 | 0.71 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.71 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.71 |
| ▸ | BLM | P54132 | 3/20 | 0.71 |
| ▸ | LMNA | P02545 | 3/20 | 0.71 |
| ▸ | MEN1 | O00255 | 3/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.71 |
| ▸ | RXRB | P28702 | 2/20 | 0.71 |
| ▸ | RXRG | P48443 | 2/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1362317 | 0.91 | ALDH1A1 (0.80) | ALDH1A1MAPTCYP3A4RXRARARA | |
| SCHEMBL11407606 | 0.89 | ALDH1A1 (0.64) | ALDH1A1MAPTCYP3A4RXRARARA | |
| SCHEMBL21587 | 0.89 | ALDH1A1 (0.77) | ALDH1A1MAPTCYP3A4RXRARARA | |
| SCHEMBL4862741 | 0.89 | ALDH1A1 (0.77) | ALDH1A1MAPTCYP3A4RXRARARA | |
| SCHEMBL11125160 | 0.89 | ALDH1A1 (0.77) | ALDH1A1MAPTCYP3A4RXRARARA | |
| SCHEMBL7523937 | 0.89 | ALDH1A1 (0.77) | ALDH1A1MAPTCYP3A4RXRARARA | |
| SCHEMBL5225545 | 0.89 | ALDH1A1 (0.77) | ALDH1A1MAPTCYP3A4RXRARARA | |
| SCHEMBL7890783 | 0.89 | ALDH1A1 (0.77) | ALDH1A1MAPTCYP3A4RXRARARA | |
| SCHEMBL3255 | 0.89 | ALDH1A1 (0.67) | ALDH1A1MAPTCYP3A4RXRARARA | |
| SCHEMBL4903545 | 0.89 | ALDH1A1 (0.67) | ALDH1A1MAPTCYP3A4RXRARARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1342471-B1 | Nanocapsules based on polyol polyester, and cosmetic and dermatological compositions containing same | OREAL (FR) | 2005-06-08 | — | — | EP | claimed |
| US-20030224060-A1 | Polyester polyol nanocapsules, compositions thereof, and methods of use | L'OREAL (FR) | 2003-12-04 | — | — | US | claimed |
| US-20080221349-A1 | Preparation of Amides of Retinoic Acid Via Mixed Anhydride and Mixed Carbonate Intermediates | CEDARBURG PHARMACEUTICALS, INC. | 2008-09-11 | — | — | US | disclosed |
| US-7321064-B1 | Preparation of amides of retinoic acid via mixed anhydride and mixed carbonate intermediates | CEDARBURG PHARMACEUTICALS, INC. (US) | 2008-01-22 | — | — | US | disclosed |
| US-20030224060-A1 | Polyester polyol nanocapsules, compositions thereof, and methods of use | L'OREAL (FR) | 2003-12-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080221349-A1 | Preparation of Amides of Retinoic Acid Via Mixed Anhydride and Mixed Carbonate Intermediates | RARA, RARB, RARG | ALDH1A1 784/4885MAPT 3488/4885CYP3A4 354/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.