Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CETP | P11597 | 1/20 | 0.35 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.31 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7121163 | 0.85 | CETP (0.36) | CETPPTGDRPTGDR2 | |
| SCHEMBL6422219 | 0.85 | CETP (0.37) | CETPPTGDRPTGDR2 | |
| SCHEMBL6422216 | 0.85 | CETP (0.37) | CETPPTGDRPTGDR2 | |
| SCHEMBL6444187 | 0.84 | — | — | |
| SCHEMBL6424437 | 0.83 | CETP (0.36) | CETPPTGDRPTGDR2 | |
| SCHEMBL7120050 | 0.73 | GCGR (0.36) | CETP | |
| SCHEMBL7124749 | 0.72 | GCGR (0.39) | CETP | |
| SCHEMBL6477347 | 0.71 | CETP (0.49) | CETP | |
| SCHEMBL6527592 | 0.71 | CETP (0.57) | CETP | |
| SCHEMBL6475752 | 0.71 | CETP (0.47) | CETP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1017659-B1 | SUBSTITUTED TETRAHYDRONAPHTHALINE AND ANALOGOUS COMPOUNDS | BAYER HEALTHCARE AG (DE) | 2005-04-27 | — | — | EP | disclosed |
| US-6586613-B1 | Compounds such as 5-(tert-butyldimethylsiloxy)-7,7-dimethyl -4(4-fluorophenyl)-3-(hydroxy-(4-trifluorophenyl)-methyl)-2-isopropyl -5,6,7,8-tetrahydronaphthalene, used as antagonists for cholesteryl ester transferase protein; hyperlipemia | BAYER AKTIENGELLSCHAFT (DE) | 2003-07-01 | — | — | US | disclosed |