Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CETP | P11597 | 1/20 | 0.36 |
| ▸ | SSTR5 | P35346 | 4/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.32 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.32 |
| ▸ | PTPRB | P23467 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | SLC34A1 | Q06495 | 1/20 | 0.30 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.30 |
| ▸ | FEN1 | P39748 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7121163 | 0.85 | CETP (0.36) | CETPSSTR5PTGDR2PTGDRPTPRB | |
| SCHEMBL6421617 | 0.84 | CETP (0.42) | CETPSSTR5PTGDR2PTGDRCNR2 | |
| SCHEMBL6422219 | 0.83 | CETP (0.37) | CETPSSTR5PTGDR2PTGDRPTPRB | |
| SCHEMBL6422216 | 0.83 | CETP (0.37) | CETPSSTR5PTGDR2PTGDRPTPRB | |
| SCHEMBL6424280 | 0.83 | CETP (0.35) | CETPPTGDR2PTGDR | |
| SCHEMBL7124749 | 0.77 | GCGR (0.39) | CETP | |
| SCHEMBL6422071 | 0.77 | ALPL (0.35) | CETPSSTR5PTGDR2PTGDRCNR2 | |
| SCHEMBL7129152 | 0.76 | GCGR (0.38) | — | |
| SCHEMBL6381544 | 0.75 | GCGR (0.35) | SSTR5 | |
| SCHEMBL7129129 | 0.75 | GCGR (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1017659-B1 | SUBSTITUTED TETRAHYDRONAPHTHALINE AND ANALOGOUS COMPOUNDS | BAYER HEALTHCARE AG (DE) | 2005-04-27 | — | — | EP | disclosed |