SCHEMBL6426034

SCHEMBL6426034

O=C(Nc1ccc(C(=O)O)c(C(=O)O)c1)c1ccc(C(=O)O)c(C(=O)O)c1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.58
PKM P14618 4/20 0.58
HPSE Q9Y251 2/20 0.57
MEN1 O00255 2/20 0.56
TDP1 Q9NUW8 4/20 0.56
NPC1 O15118 2/20 0.51
MAPT P10636 2/20 0.51
RAB9A P51151 2/20 0.51
KDM4E B2RXH2 1/20 0.51
NR1H4 Q96RI1 1/20 0.51
ALDH1A1 P00352 2/20 0.51
CYP1A2 P05177 2/20 0.51
GALK1 P51570 1/20 0.51
CASP6 P55212 1/20 0.51
MCL1 Q07820 1/20 0.51
PLEC Q15149 1/20 0.51
HPGD P15428 1/20 0.51
CDC25A P30304 1/20 0.50
CDC25B P30305 1/20 0.50
HSD17B10 Q99714 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3757836 0.91 KMT2A (0.69) KMT2APKMHPSEMEN1TDP1
SCHEMBL25452049 0.89 PTPN1 (0.59) KMT2APKMHPSEMEN1TDP1
SCHEMBL11650061 0.87 KMT2A (0.57) KMT2APKMHPSEMEN1TDP1
SCHEMBL11593167 0.87 KMT2A (0.76) KMT2APKMHPSEMEN1TDP1
SCHEMBL11590256 0.86 NPC1 (0.66) KMT2APKMHPSEMEN1TDP1
SCHEMBL11593027 0.86 NPC1 (0.59) KMT2APKMHPSEMEN1TDP1
SCHEMBL28308170 0.84 KMT2A (0.51) KMT2APKMHPSEMEN1TDP1
SCHEMBL7052264 0.84 KMT2A (0.63) KMT2AHPSEMEN1TDP1MAPT
SCHEMBL11592884 0.82 NPC1 (0.69) KMT2APKMHPSEMEN1TDP1
SCHEMBL12590453 0.81 ALDH1A1 (0.72) KMT2APKMMEN1ALDH1A1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6955712-B2 Proton-conducting polymer with acid groups in side chains, preparation method thereof, polymer membrane manufactured using the polymer, and fuel cell using the polymer membrane SAMSUNG SDI CO., LTD. (KR) 2005-10-18 US disclosed
US-20040097695-A1 Proton-conducting polymer with acid groups in side chains, preparation method thereof, polymer membrane manufactured using the polymer, and fuel cell using the polymer membrane SAMSUNG SDI CO., LTD. (KR) 2004-05-20 US disclosed
US-6596838-B1 Electrodialysis, electroosmosis, reverse osmosis COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) 2003-07-22 US disclosed
US-6425944-B2 DURABILITY; ELECTRIC VEHICLES; SPACECRAFT; ION EXCHANGERS; THIN FILMS COMMISSRIAT A L'ENERGIE ATOMIQUE (FR) 2002-07-30 US disclosed
US-6376129-B2 ION EXCHANGE MEMBRANE; POWER SOURCE FOR ELECTRICITY VEHICLES COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) 2002-04-23 US disclosed
US-20010020082-A1 Sulphonated polyimides, membranes prepared with them, and a fuel cell device that includes these membranes FAURE SYLVAIN (FR) 2001-09-06 US disclosed
US-20010019787-A1 Sulphonated polyimides, membranes prepared with them, and a fuel cell device that includes these membranes FAURE SYLVAIN (FR) 2001-09-06 US disclosed
US-6245881-B1 SULFONATED AROMATIC POLYIMIDES; DURABLE ION EXCHANGE MEMBRANES SUITABLE FOR FUEL CELLS IN ELECTRIC VEHICLES COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) 2001-06-12 US disclosed
US-4720539-A Polyimide precursor compositions, their manufacture, the resultant polyimides and their use, particularly for manufacturing enamelling varnishes for electric wires CENTRE D'ETUDES DES MATERIAUX ORGANIQUES POUR TECHNOLOGIES AVANCEES (FR) 1988-01-19 US disclosed