Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP24A1 | Q07973 | 12/20 | 0.40 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.33 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.31 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.30 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6425946 | 0.84 | ENPP2 (0.33) | KDM4C | |
| SCHEMBL6427406 | 0.83 | ENPP2 (0.33) | KDM4C | |
| SCHEMBL6427753 | 0.83 | KDM4E (0.37) | — | |
| SCHEMBL6428560 | 0.82 | ENPP2 (0.32) | KDM4C | |
| SCHEMBL6427836 | 0.82 | ENPP2 (0.32) | — | |
| SCHEMBL6426342 | 0.81 | ENPP2 (0.31) | — | |
| SCHEMBL6425803 | 0.81 | ENPP2 (0.32) | KDM4C | |
| SCHEMBL6428655 | 0.81 | TUBB4A (0.32) | KDM4C | |
| SCHEMBL6426059 | 0.81 | KDM4C (0.32) | KDM4C | |
| SCHEMBL6430160 | 0.81 | ENPP2 (0.31) | KDM4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050261339-A1 | Pyrazole compound and medicinal composition containing the same | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2005-11-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050261339-A1 | Pyrazole compound and medicinal composition containing the same | CNKSR1, NR3C2, CSNK2B | CYP24A1 1981/4885CYP26A1 850/4885CYP17A1 1039/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.