Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM7 | Q14831 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL6503442 | 0.94 | GRM7 (0.44) | GRM7LMNAMAPTPOLBKMT2A | |
| SCHEMBL6428624 | 0.87 | GRM7 (0.45) | GRM7LMNAMAPTKMT2ANPSR1 | |
| SCHEMBL6507627 | 0.86 | GRM7 (0.46) | GRM7MAPTPOLBKMT2ANPSR1 | |
| SCHEMBL6428159 | 0.86 | GRM7 (0.46) | GRM7MAPTPOLBKMT2ANPSR1 | |
| SCHEMBL6428309 | 0.83 | GRM7 (0.46) | GRM7MAPTPOLBALDH1A1SMN1; SMN2 | |
| SCHEMBL6427597 | 0.81 | ALDH1A1 (0.47) | GRM7LMNAMAPTPOLBKMT2A | |
| SCHEMBL6508360 | 0.81 | ALDH1A1 (0.47) | GRM7LMNAMAPTKMT2ANPSR1 | |
| SCHEMBL6502545 | 0.81 | TSHR (0.53) | GRM7MAPTPOLBKMT2ANPSR1 | |
| SCHEMBL6506436 | 0.81 | TSHR (0.53) | GRM7MAPTPOLBKMT2ANPSR1 | |
| SCHEMBL6500660 | 0.81 | TSHR (0.53) | GRM7MAPTPOLBKMT2ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005075471-A2 | THIAZOL-COMPOUNDS AS 11-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 1 INHIBITORS | BIOVITRUM AB (SE) | 2005-08-18 | — | — | WO | claimed |