Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | GRM7 | Q14831 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6500660 | 1.00 | TSHR (0.53) | TSHRSMN1; SMN2NPC1RAB9APOLB | |
| SCHEMBL6506436 | 1.00 | TSHR (0.53) | TSHRSMN1; SMN2NPC1RAB9APOLB | |
| SCHEMBL6426935 | 0.95 | SMN1; SMN2 (0.51) | TSHRSMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL1605788 | 0.87 | TSHR (0.46) | TSHRSMN1; SMN2NPC1RAB9APOLB | |
| SCHEMBL6507627 | 0.86 | GRM7 (0.46) | TSHRSMN1; SMN2NPC1RAB9APOLB | |
| SCHEMBL6428159 | 0.86 | GRM7 (0.46) | TSHRSMN1; SMN2NPC1RAB9APOLB | |
| SCHEMBL6428309 | 0.84 | GRM7 (0.46) | TSHRSMN1; SMN2POLBALDH1A1KDM4E | |
| SCHEMBL6426470 | 0.84 | ALDH1A1 (0.41) | TSHRSMN1; SMN2POLBALDH1A1KDM4E | |
| SCHEMBL6427597 | 0.83 | ALDH1A1 (0.47) | TSHRSMN1; SMN2POLBALDH1A1KDM4E | |
| SCHEMBL6507694 | 0.83 | ALDH1A1 (0.46) | SMN1; SMN2POLBALDH1A1KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050239853-A1 | New compounds | BIOVITRUM AB (SE) | 2005-10-27 | — | — | US | claimed |
| US-20050239853-A1 | New compounds | BIOVITRUM AB (SE) | 2005-10-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050239853-A1 | New compounds | HSD11B1, CYP11B1, HSD3B1 | TSHR 2078/4885SMN1; SMN2 3733/4885NPC1 277/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.