Styrene

Styrene

SCHEMBL6426317

C=C(C)C(=O)OCl.C=Cc1ccccc1

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.50
TSHR P16473 2/20 0.50
ELANE P08246 1/20 0.42
AKR1C3 P42330 1/20 0.40
GLA P06280 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
HDAC3 O15379 1/20 0.38
TNKS O95271 1/20 0.38
HDAC4 P56524 1/20 0.38
HDAC1 Q13547 1/20 0.38
HCAR2 Q8TDS4 1/20 0.38
HDAC7 Q8WUI4 1/20 0.38
HDAC2 Q92769 1/20 0.38
HDAC10 Q969S8 1/20 0.38
HDAC11 Q96DB2 1/20 0.38
HDAC8 Q9BY41 1/20 0.38
TNKS2 Q9H2K2 1/20 0.38
HDAC6 Q9UBN7 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Styrene SCHEMBL9639818 0.86 ALDH1A1 (0.54) ALDH1A1TSHRELANEAKR1C3GLA
Styrene SCHEMBL35776 0.86 ALDH1A1 (0.54) ALDH1A1TSHRELANEAKR1C3GLA
Styrene SCHEMBL11805811 0.86 ALDH1A1 (0.54) ALDH1A1TSHRELANEAKR1C3GLA
Styrene SCHEMBL28292797 0.86 ALDH1A1 (0.54) ALDH1A1TSHRELANEAKR1C3GLA
Styrene SCHEMBL8576362 0.86 ALDH1A1 (0.54) ALDH1A1TSHRELANEAKR1C3GLA
Styrene SCHEMBL678464 0.86 ALDH1A1 (0.54) ALDH1A1TSHRELANEAKR1C3GLA
Styrene SCHEMBL9182393 0.86 ALDH1A1 (0.54) ALDH1A1TSHRELANEAKR1C3GLA
Styrene SCHEMBL28445740 0.84 ALDH1A1 (0.52) ALDH1A1TSHRELANEAKR1C3GLA
Styrene SCHEMBL27467738 0.84 ALDH1A1 (0.48) ALDH1A1TSHRELANEAKR1C3GLA
Styrene SCHEMBL27480098 0.84 ALDH1A1 (0.52) ALDH1A1TSHRELANEAKR1C3GLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6939654-B2 Carrier and developer for developing latent electrostatic images RICOH COMPANY, LTD. (JP) 2005-09-06 US disclosed
US-20040142269-A1 Carrier and developer for developing latent electrostatic images RICOH COMPANY, LTD. (JP) 2004-07-22 US disclosed