Styrene

Styrene

SCHEMBL678464

C=C(C)C(=O)OC.C=C(C)C(=O)OC.C=Cc1ccccc1

nearest known ligand 0.55

Full drug profile on Sugi Atlas →

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.54
TSHR P16473 1/20 0.50
ELANE P08246 1/20 0.42
LMNA P02545 2/20 0.41
KDM4E B2RXH2 2/20 0.41
POLB P06746 1/20 0.41
MAPT P10636 1/20 0.41
HTT P42858 1/20 0.41
AKR1C3 P42330 1/20 0.40
GLA P06280 1/20 0.40
TDP1 Q9NUW8 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Styrene SCHEMBL11805811 1.00 ALDH1A1 (0.54) ALDH1A1TSHRELANELMNAKDM4E
Styrene SCHEMBL9639818 1.00 ALDH1A1 (0.54) ALDH1A1TSHRELANELMNAKDM4E
Styrene SCHEMBL9182393 1.00 ALDH1A1 (0.54) ALDH1A1TSHRELANELMNAKDM4E
Styrene SCHEMBL28292797 1.00 ALDH1A1 (0.54) ALDH1A1TSHRELANELMNAKDM4E
Styrene SCHEMBL35776 1.00 ALDH1A1 (0.54) ALDH1A1TSHRELANELMNAKDM4E
Styrene SCHEMBL8576362 1.00 ALDH1A1 (0.54) ALDH1A1TSHRELANELMNAKDM4E
Styrene SCHEMBL27480098 0.98 ALDH1A1 (0.52) ALDH1A1TSHRELANELMNAKDM4E
Styrene SCHEMBL28190634 0.98 ALDH1A1 (0.52) ALDH1A1TSHRELANELMNAKDM4E
Styrene SCHEMBL27818320 0.98 ALDH1A1 (0.52) ALDH1A1TSHRELANELMNAKDM4E
Styrene SCHEMBL28445740 0.98 ALDH1A1 (0.52) ALDH1A1TSHRELANELMNAKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101090905-B Organobismuth compound, process for producing the same, living radical polymerization initiator, process for producing polymer using the initiator, and polymer OTSUKA CHEMICAL CO.,LTD. (JP) 2012-02-15 CN disclosed
US-20110275774-A1 ORGANOANTIMONY COMPOUND, PROCESS FOR PREPARING SAME, LIVING RADICAL POLYMERIZATION INITIATOR, PROCESS FOR PRODUCING POLYMER WITH USE OF SAME, AND THE POLYMER YAMAGO SHIGERU 2011-11-10 US disclosed
EP-1595894-B1 PROCESS FOR THE PRODUCTION OF LIVING RADICAL POLYMERS OTSUKA CHEMICAL CO LTD (JP) 2011-10-12 EP disclosed
US-8008414-B2 Organic antimony compound, process for producing the same, living radical polymerization initiator, process for producing polymer using the same, and polymer OTSUKA CHEMICAL CO., LTD. (JP) 2011-08-30 US disclosed
EP-1829883-B1 ORGANIC BISMUTH COMPOUND, METHOD FOR PRODUCING SAME, LIVING RADICAL POLYMERIZATION INITIATOR, METHOD FOR PRODUCING POLYMER USING SAME, AND POLYMER OTSUKA CHEMICAL CO LTD (JP) 2011-08-17 EP disclosed
EP-1767539-B1 ORGANIC ANTIMONY COMPOUND, PROCESS FOR PRODUCING THE SAME, LIVING RADICAL POLYMERIZATION INITIATOR, PROCESS FOR PRODUCING POLYMER USING THE SAME, AND POLYMER OTSUKA CHEMICAL CO LTD (JP) 2011-07-27 EP disclosed
CN-101076534-B Organic antimony compound, process for producing the same, living radical polymerization initiator, process for producing polymer using the initiator, and polymer OTSUKA CHEMICAL CO LTD 2011-06-22 CN disclosed
US-7847043-B2 Organic bismuth compound, method for producing same, living radical polymerization initiator, method for producing polymer using same, and polymer OTSUKA CHEMICAL CO., LTD. (JP) 2010-12-07 US disclosed
CN-1820030-B Process for the production of living radical polymers and polymers OTSUKA CHEMICAL CO LTD 2010-10-06 CN disclosed
US-20090299008-A1 Organic antimony compound, process for producing the same, living radical polymerization initiator, process for producing polymer using the same, and polymer OTSUKA CHEMICAL CO., LTD. (JP) 2009-12-03 US disclosed
EP-1767539-A1 ORGANIC ANTIMONY COMPOUND, PROCESS FOR PRODUCING THE SAME, LIVING RADICAL POLYMERIZATION INITIATOR, PROCESS FOR PRODUCING POLYMER USING THE SAME, AND POLYMER OTSUKA CHEMICAL COMPANY, LTD. (JP) 2007-03-28 EP disclosed
US-20060199927-A1 Process for production of living-radical polymers and polymers Outdoor Wireless Networks LLC 2006-09-07 US disclosed
CN-1820030-A Process for the production of living radical polymers and polymers OTSUKA CHEMICAL CO LTD (JP) 2006-08-16 CN disclosed
US-20060167199-A1 Process for produciton of living radical polymers and polymers OTSUKA CHEMICAL CO., LTD. (JP) 2006-07-27 US disclosed
US-20060135711-A1 Process for the production of living radical polymers and polymers OTSUKA CHEMICAL CO., LTD. (JP) 2006-06-22 US disclosed
CN-1735657-A Stabilization of thermoplastic nanocomposites CIBA SC HOLDING AG (CH) 2006-02-15 CN disclosed
EP-1595894-A1 PROCESS FOR THE PRODUCTION OF LIVING RADICAL POLYMERS AND POLYMERS OTSUKA CHEMICAL COMPANY, LIMITED (JP) 2005-11-16 EP disclosed
EP-1541592-A1 PROCESS FOR PRODUCTION OF LIVING RADICAL POLYMERS AND POLYMERS OTSUKA CHEMICAL COMPANY, LIMITED (JP) 2005-06-15 EP disclosed
CN-1152903-C Solvent-free, radiation-curable, optical glass fiber coating compsn. and solvent-free method for making solvent-free, radiation-curable, optical glass fiber coating compsn. DSM 2004-06-09 CN disclosed
CN-1205718-A Solvent-free, radiation-curable optical glass fiber coating composition and method for making same DSM NV (NL) 1999-01-20 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060135711-A1 Process for the production of living radical polymers and polymers CBR3, CBR1, CCNT1 ALDH1A1 483/4885TSHR 3860/4885ELANE 2110/4885
US-20090299008-A1 Organic antimony compound, process for producing the same, living radical polymerization initiator, process for producing polymer using the same, and polymer AOC2, ODC1, MCM7 ALDH1A1 1542/4885TSHR 2137/4885ELANE 3578/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.