Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5494715 | 0.90 | ITGB3 (0.36) | KMT2AKDM4ELMNAALDH1A1NTRK1 | |
| SCHEMBL6425375 | 0.89 | LPAR1 (0.36) | MEN1KMT2AL3MBTL1LPAR1LMNA | |
| SCHEMBL27620815 | 0.85 | CYP3A4 (0.44) | — | |
| SCHEMBL5496615 | 0.84 | HDAC1 (0.40) | HDAC3HDAC1 | |
| SCHEMBL5496538 | 0.83 | HDAC3 (0.43) | HDAC3HDAC1 | |
| SCHEMBL27620832 | 0.83 | CETP (0.44) | KMT2AL3MBTL1KDM4ELMNAALDH1A1 | |
| SCHEMBL5500962 | 0.82 | ADRA2C (0.39) | LPAR1NTRK1 | |
| SCHEMBL3111828 | 0.82 | NTRK1 (0.36) | KMT2ALPAR1LMNANTRK1 | |
| SCHEMBL6425423 | 0.82 | HPGD (0.40) | MEN1KMT2AL3MBTL1KDM4ELMNA | |
| SCHEMBL27641152 | 0.82 | SOAT1 (0.46) | KMT2AKDM4ELMNAALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1556389-A1 | CEPHEM COMPOUNDS | Astellas Pharma Inc. (JP) | 2005-07-27 | — | — | EP | disclosed |
| WO-2004039814-A1 | CEPHEM COMPOUNDS | ASTELLAS PHARMA INC. (JP) | 2004-05-13 | — | — | WO | disclosed |