Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | NAPRT | Q6XQN6 | 2/20 | 0.41 |
| ▸ | DAO | P14920 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | CA6 | P23280 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9360259 | 0.79 | ALDH1A1 (0.48) | ALDH1A1ALOX15NAPRTTSHRKDM4E | |
| SCHEMBL10743844 | 0.79 | AKR1C3 (0.48) | AKR1C3ALDH1A1ALOX15NAPRTDAO | |
| SCHEMBL2422467 | 0.78 | ALDH1A1 (0.56) | AKR1C3ALDH1A1ALOX15NAPRTTSHR | |
| SCHEMBL1805157 | 0.78 | KDM4E (0.51) | AKR1C3ALDH1A1ALOX15TSHRKDM4E | |
| SCHEMBL5491908 | 0.76 | AKR1C3 (0.46) | AKR1C3ALDH1A1ALOX15HPGDSMN1; SMN2 | |
| SCHEMBL14718826 | 0.75 | ALDH1A1 (0.52) | AKR1C3ALDH1A1ALOX15NAPRTTSHR | |
| SCHEMBL27727976 | 0.75 | ALDH1A1 (0.52) | AKR1C3ALDH1A1ALOX15NAPRTTSHR | |
| SCHEMBL9575319 | 0.74 | LTB4R2 (0.46) | AKR1C3ALDH1A1ALOX15NAPRTDAO | |
| SCHEMBL13066508 | 0.73 | ALDH1A1 (0.62) | AKR1C3ALDH1A1ALOX15NAPRTTSHR | |
| SCHEMBL6426612 | 0.73 | ALDH1A1 (0.41) | AKR1C3ALDH1A1ALOX15NAPRTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1212056-B1 | METHODS AND COMPOSITIONS FOR BISUBSTRATE INHIBITORS OF ACETYLTRANSFERASES | US GOV HEALTH & HUMAN SERV (US) | 2005-12-07 | — | — | EP | disclosed |