Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 1/20 | 0.54 |
| ▸ | PAOX | Q6QHF9 | 8/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | CASP2 | P42575 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3240257 | 0.98 | ADRA1A (0.57) | ADRA1APAOXMAPK1KDM4EHIF1A | |
| SCHEMBL854713 | 0.93 | ADRA1A (0.45) | ADRA1APAOXMAPK1KDM4EHIF1A | |
| SCHEMBL13902111 | 0.83 | KDM4E (0.71) | ADRA1APAOXMAPK1KDM4EHIF1A | |
| SCHEMBL8700639 | 0.82 | PAOX (0.53) | ADRA1APAOXMAPK1KDM4EHIF1A | |
| SCHEMBL6894584 | 0.82 | — | — | |
| SCHEMBL3174690 | 0.82 | KDM4E (0.50) | ADRA1APAOXMAPK1KDM4EHIF1A | |
| SCHEMBL24572062 | 0.81 | KDM4E (0.76) | ADRA1APAOXMAPK1KDM4EHIF1A | |
| SCHEMBL16318219 | 0.81 | KDM4E (0.76) | ADRA1APAOXMAPK1KDM4EHIF1A | |
| SCHEMBL7046977 | 0.81 | KDM4E (0.76) | ADRA1APAOXMAPK1KDM4EHIF1A | |
| SCHEMBL17445713 | 0.81 | KDM4E (0.76) | ADRA1APAOXMAPK1KDM4EHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1286673-B8 | LIGANDS OF INTEGRIN RECEPTORS | ABBOTT GMBH & CO KG (DE) | 2005-07-20 | — | — | EP | disclosed |
| EP-1286673-B1 | LIGANDS OF INTEGRIN RECEPTORS | BASF AG (DE) | 2005-05-25 | — | — | EP | disclosed |
| EP-1307443-A2 | NOVEL SUBSTITUTED DIARYL AZEPINE DERIVATIVES AS INTEGRIN LIGANDS | BASF AKTIENGESELLSCHAFT (DE) | 2003-05-07 | — | — | EP | disclosed |
| EP-1286673-A2 | LIGANDS OF INTEGRIN RECEPTORS | Basf Aktiengesellschaft (DE) | 2003-03-05 | — | — | EP | disclosed |
| WO-2002051810-A2 | INTEGRIN RECEPTOR LIGANDS | ABBOTT GMBH & CO. KG (DE) | 2002-07-04 | — | — | WO | disclosed |
| WO-2002014320-A2 | NOVEL SUBSTITUTED DIARYL AZEPINE DERIVATIVES AS INTEGRIN LIGANDS | BASF AKTIENGESELLSCHAFT (DE) | 2002-02-21 | — | — | WO | disclosed |
| WO-2001093840-A2 | LIGANDS OF INTEGRIN RECEPTORS | BASF AG (DE) | 2001-12-13 | — | — | WO | disclosed |