Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 4/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
| ▸ | USP28 | Q96RU2 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4872003 | 0.86 | POLB (0.36) | POLBHPGDGAAALOX15ALDH1A1 | |
| SCHEMBL4984472 | 0.84 | ALDH1A1 (0.34) | POLBHPGDGAAALOX15ALDH1A1 | |
| SCHEMBL6427390 | 0.84 | POLB (0.33) | POLBHPGDGAAALOX15ALDH1A1 | |
| SCHEMBL4984475 | 0.83 | ALDH1A1 (0.33) | POLBHPGDGAAALOX15ALDH1A1 | |
| SCHEMBL14019595 | 0.81 | POLB (0.39) | POLBHPGDGAAALOX15ALDH1A1 | |
| Hydrochloric Acid SCHEMBL4873425 | 0.80 | POLB (0.39) | POLBHPGDGAAALOX15ALDH1A1 | |
| SCHEMBL4874627 | 0.79 | ALDH1A1 (0.39) | GAAALDH1A1KMT2ATSHRAOC3 | |
| Carbamic Acid SCHEMBL4872027 | 0.78 | AOC3 (0.37) | POLBHPGDGAAALOX15AOC3 | |
| SCHEMBL4991683 | 0.78 | ALDH1A1 (0.38) | GAAALDH1A1KMT2AMAPTTSHR | |
| SCHEMBL6390501 | 0.77 | GHSR (0.39) | HPGDALDH1A1AOC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1608365-A1 | METHOD FOR TREATING VASCULAR HYPERPERMEABLE DISEASE | Sucampo AG (CH) | 2005-12-28 | — | — | EP | disclosed |
| WO-2004087138-A1 | METHOD FOR TREATING VASCULAR HYPERPERMEABLE DISEASE | SUCAMPO AG (CH) | 2004-10-14 | — | — | WO | disclosed |