Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | PARP1 | P09874 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | F2 | P00734 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | CES1 | P23141 | 3/20 | 0.42 |
| ▸ | CES2 | O00748 | 2/20 | 0.42 |
| ▸ | DAO | P14920 | 1/20 | 0.42 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL64274 | 0.91 | TDP1 (0.52) | TSHRPOLBTDP1MAPTL3MBTL1 | |
| SCHEMBL30629348 | 0.84 | TDP1 (0.48) | TSHRPOLBTDP1MAPTL3MBTL1 | |
| SCHEMBL11680003 | 0.83 | L3MBTL1 (0.52) | TSHRPOLBTDP1MAPTL3MBTL1 | |
| Terephthalic Acid SCHEMBL27838304 | 0.83 | TSHR (0.61) | TSHRPOLBTDP1MAPTL3MBTL1 | |
| SCHEMBL11322544 | 0.82 | TDP1 (0.48) | TSHRPOLBTDP1MAPTL3MBTL1 | |
| SCHEMBL2146344 | 0.82 | TDP1 (0.48) | TSHRPOLBTDP1MAPTL3MBTL1 | |
| Malonic Acid SCHEMBL27909909 | 0.81 | TDP1 (0.46) | TSHRPOLBTDP1MAPTL3MBTL1 | |
| SCHEMBL27963230 | 0.81 | MEN1 (0.47) | TSHRPOLBTDP1MAPTL3MBTL1 | |
| Succinic Acid SCHEMBL27852517 | 0.81 | NR4A2 (0.57) | TSHRPOLBTDP1MAPTL3MBTL1 | |
| SCHEMBL5574638 | 0.80 | TSHR (0.52) | TSHRPOLBTDP1MAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5110986-A | Reaction of a 1,3,4-oxadiazole with a tert-alkyl cation precursor in presence of strong acid catalyst | ROHM AND HAAS COMPANY (US) | 1992-05-05 | — | — | US | disclosed |