Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 3/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | TCF4 | P15884 | 2/20 | 0.32 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.32 |
| ▸ | CDH1 | P12830 | 1/20 | 0.32 |
| ▸ | APC | P25054 | 1/20 | 0.32 |
| ▸ | TCF7L2 | Q9NQB0 | 1/20 | 0.32 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 5/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 5/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2214744 | 0.84 | ALOX5 (0.39) | ALOX5NFKB1NFKB2RELASMPD1 | |
| SCHEMBL28508824 | 0.72 | ALOX5 (0.36) | ALOX5KMT2AKDM4EGAATNKS2 | |
| SCHEMBL2270174 | 0.71 | SMPD1 (0.37) | ALOX5NFKB1NFKB2RELASMPD1 | |
| SCHEMBL28499468 | 0.70 | ALOX5 (0.42) | ALOX5KDM4EGAA | |
| SCHEMBL2209075 | 0.70 | KDM4E (0.38) | ALOX5KMT2AKDM4EGAAMEN1 | |
| SCHEMBL28500686 | 0.69 | ALOX5 (0.46) | ALOX5 | |
| SCHEMBL2214661 | 0.69 | SMPD1 (0.40) | ALOX5NFKB1NFKB2RELASMPD1 | |
| SCHEMBL2215829 | 0.69 | ALOX5 (0.48) | ALOX5 | |
| SCHEMBL28500590 | 0.69 | ALOX5 (0.48) | ALOX5 | |
| SCHEMBL28503969 | 0.69 | ALOX5 (0.48) | ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1591099-A2 | Methods for stabilizing ingredients within cosmetics, personal care and household products | MERCK PATENT GmbH (DE) | 2005-11-02 | — | — | EP | disclosed |