Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | AKT1 | P31749 | 2/20 | 0.32 |
| ▸ | TCF4 | P15884 | 2/20 | 0.31 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.31 |
| ▸ | CDH1 | P12830 | 1/20 | 0.31 |
| ▸ | APC | P25054 | 1/20 | 0.31 |
| ▸ | TCF7L2 | Q9NQB0 | 1/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.31 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2270174 | 0.87 | SMPD1 (0.37) | ALOX5NFKB1NFKB2RELASMPD1 | |
| SCHEMBL6427404 | 0.84 | ALOX5 (0.41) | ALOX5NFKB1NFKB2RELASMPD1 | |
| SCHEMBL28508824 | 0.84 | ALOX5 (0.36) | ALOX5GAAKDM4EKMT2A | |
| SCHEMBL2214661 | 0.83 | SMPD1 (0.40) | ALOX5NFKB1NFKB2RELASMPD1 | |
| SCHEMBL28499468 | 0.82 | ALOX5 (0.42) | ALOX5GAAKDM4E | |
| SCHEMBL28500686 | 0.81 | ALOX5 (0.46) | ALOX5 | |
| SCHEMBL2215829 | 0.80 | ALOX5 (0.48) | ALOX5 | |
| SCHEMBL28506293 | 0.80 | ALOX5 (0.48) | ALOX5 | |
| SCHEMBL28503969 | 0.80 | ALOX5 (0.48) | ALOX5 | |
| SCHEMBL28500590 | 0.80 | ALOX5 (0.48) | ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 105 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1635777-B1 | PHOTOSTABLE ORGANIC SUNSCREEN COMPOSITION | MERCK PATENT GMBH (DE) | 2012-06-06 | — | — | EP | claimed |
| US-8003082-B2 | Photostable organic sunscreen composition | MERCK PATENT GMBH (DE) | 2011-08-23 | — | — | US | claimed |
| EP-1747773-B1 | Photostable organic sunscreen compositions with antioxidant properties | MERCK PATENT GMBH (DE) | 2010-08-04 | — | — | EP | claimed |
| US-20100047185-A1 | ACTVIE SUBSTANCE COMBINATION | ISDIN S.A. (ES) | 2010-02-25 | — | — | US | claimed |
| WO-2008083975-A1 | LIGHT-STABILIZED COMPOSITION | ISDIN S.A. (ES) | 2008-07-17 | — | — | WO | claimed |
| WO-2008083974-A1 | ACTIVE SUBSTANCE COMBINATION | ISDIN S.A. (ES) | 2008-07-17 | — | — | WO | claimed |
| WO-2008067928-A1 | UV ABSORBING COMPOSITIONS CONTAINING A PYRROLYLTRIAZINE | ISDIN S.A. (ES) | 2008-06-12 | — | — | WO | claimed |
| US-20080131381-A1 | METHODS FOR PHOTOSTABILIZING INGREDIENTS WITHIN COSMETICS, PERSONAL CARE AND HOUSEHOLD PRODUCTS AND COMPOSITIONS OBTAINED THEREFROM | MERCK PATENT GESELLSCHAFT (DE) | 2008-06-05 | — | — | US | claimed |
| US-20070059258-A1 | Photostable organic sunscreen composition | MERCK PATENT GMBH (DE) | 2007-03-15 | — | — | US | claimed |
| EP-1747773-A2 | Photostable organic sunscreen compositions with antioxidant properties | Merck Patent GmbH (DE) | 2007-01-31 | — | — | EP | claimed |
| EP-1406582-B1 | PHOTOSTABLE ORGANIC SUNSCREEN COMPOUNDS WITH ANTIOXIDANT PROPERTIES AND COMPOSITIONS OBTAINED THEREFROM | MERCK PATENT GMBH (DE) | 2006-10-25 | — | — | EP | claimed |
| EP-1635777-A1 | PHOTOSTABLE ORGANIC SUNSCREEN COMPOSITION | MERCK PATENT GmbH (DE) | 2006-03-22 | — | — | EP | claimed |
| US-20050244349-A1 | Methods for stabilizing ingredients within cosmetics, personal care and household products | SUSONITY Commercial GmbH (DE) | 2005-11-03 | — | — | US | claimed |
| EP-1591099-A2 | Methods for stabilizing ingredients within cosmetics, personal care and household products | MERCK PATENT GmbH (DE) | 2005-11-02 | — | — | EP | claimed |
| WO-2004105712-A1 | PHOTOSTABLE ORGANIC SUNSCREEN COMPOSITION | MERCK PATENT GMBH (DE) | 2004-12-09 | — | — | WO | claimed |
| US-20040247536-A1 | Photo stable organic sunscreen compositions | EMD CHEMICALS, INC. | 2004-12-09 | — | — | US | claimed |
| EP-1406582-A1 | PHOTOSTABLE ORGANIC SUNSCREEN COMPOUNDS WITH ANTIOXIDANT PROPERTIES AND COMPOSITIONS OBTAINED THEREFROM | MERCK PATENT GmbH (DE) | 2004-04-14 | — | — | EP | claimed |
| US-6602515-B2 | Alpha-acetyl-3,5-dimethoxy-4-hydroxy cinnamate ester; dipalmitoyl-3,5- dimethoxy-4-hydroxy benzylidene malonate or amide derivatives | EM INDUSTRIES | 2003-08-05 | — | — | US | claimed |
| US-20030108492-A1 | PHOTO STABLE ORGANIC SUNSCREEN COMPOUNDS WITH ANTIOXIDANT PROPERTIES AND COMPOSITIONS OBTAINED THEREFROM | EM INDUSTRIES | 2003-06-12 | — | — | US | claimed |
| WO-2003007906-A1 | PHOTOSTABLE ORGANIC SUNSCREEN COMPOUNDS WITH ANTIOXIDANT PROPERTIES AND COMPOSITIONS OBTAINED THEREFROM | MERCK PATENT GMBH (DE) | 2003-01-30 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050244349-A1 | Methods for stabilizing ingredients within cosmetics, personal care and household products | CUTA, TYR, LAGE3 | ALOX5 391/4885NFKB1 1942/4885NFKB2 2717/4885 |
| US-20070059258-A1 | Photostable organic sunscreen composition | SUN2, ERCC1, PPOX | ALOX5 677/4885NFKB1 1635/4885NFKB2 1421/4885 |
| US-20100047185-A1 | ACTVIE SUBSTANCE COMBINATION | UGT2B17, TACR2, UGT1A1 | ALOX5 1030/4885NFKB1 361/4885NFKB2 356/4885 |
| US-20080131381-A1 | METHODS FOR PHOTOSTABILIZING INGREDIENTS WITHIN COSMETICS, PERSONAL CARE AND HOUSEHOLD PRODUCTS AND COMPOSITIONS OBTAINED THEREFROM | TYR, NISCH, PPOX | ALOX5 171/4885NFKB1 1920/4885NFKB2 2223/4885 |
| US-20030108492-A1 | PHOTO STABLE ORGANIC SUNSCREEN COMPOUNDS WITH ANTIOXIDANT PROPERTIES AND COMPOSITIONS OBTAINED THEREFROM | ERCC1, ERCC4, OGG1 | ALOX5 782/4885NFKB1 773/4885NFKB2 778/4885 |
| US-20040247536-A1 | Photo stable organic sunscreen compositions | SUN2, CCNB1, TYR | ALOX5 1093/4885NFKB1 985/4885NFKB2 571/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.