Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.58 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.58 |
| ▸ | SCN10A | Q9Y5Y9 | 2/20 | 0.58 |
| ▸ | CA12 | O43570 | 1/20 | 0.56 |
| ▸ | CA1 | P00915 | 1/20 | 0.56 |
| ▸ | CA2 | P00918 | 1/20 | 0.56 |
| ▸ | CA7 | P43166 | 1/20 | 0.56 |
| ▸ | CA9 | Q16790 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.56 |
| ▸ | L3MBTL3 | Q96JM7 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.54 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 3/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5322339 | 0.77 | ALDH1A1 (1.00) | ALDH1A1KMT2ACA12CA1CA2 | |
| SCHEMBL6427074 | 0.76 | ALDH1A1 (0.72) | ALDH1A1KMT2ASCN5ASCN2ASCN10A | |
| SCHEMBL6428068 | 0.74 | CA12 (0.72) | ALDH1A1KMT2ACA12CA1CA2 | |
| SCHEMBL6427542 | 0.74 | ALDH1A1 (0.69) | ALDH1A1KMT2ACA12CA1CA2 | |
| SCHEMBL26706250 | 0.74 | KMT2A (0.70) | ALDH1A1KMT2ACA12CA1CA2 | |
| SCHEMBL31349311 | 0.73 | POLB (0.76) | ALDH1A1KMT2ACA12CA1CA2 | |
| SCHEMBL6427505 | 0.72 | ALDH1A1 (0.62) | ALDH1A1KMT2ACA12CA1CA2 | |
| SCHEMBL6427605 | 0.72 | ALDH1A1 (0.66) | ALDH1A1KMT2ACA12CA1CA2 | |
| SCHEMBL31349326 | 0.72 | ALDH1A1 (0.66) | ALDH1A1KMT2ACA12CA1CA2 | |
| SCHEMBL12443384 | 0.72 | ALDH1A1 (0.62) | ALDH1A1KMT2ACA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050222408-A1 | Heterocyclic amides with anti-tuberculosis activity | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION | 2005-10-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050222408-A1 | Heterocyclic amides with anti-tuberculosis activity | TST, KAT5, NDUFS5 | ALDH1A1 2116/4885KMT2A 2545/4885SCN5A 270/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.