Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 7/20 | 0.69 |
| ▸ | CES2 | O00748 | 3/20 | 0.56 |
| ▸ | CES1 | P23141 | 2/20 | 0.56 |
| ▸ | PTGES | O14684 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.49 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.49 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6427641 | 0.89 | CYP3A4 (0.61) | ALOX5CES2CES1PTGESTP53 | |
| SCHEMBL4721016 | 0.88 | TP53 (0.67) | ALOX5CES2CES1TP53SMN1; SMN2 | |
| SCHEMBL254774 | 0.86 | CES1 (0.70) | ALOX5CES2CES1TDP1ALDH1A1 | |
| Methane SCHEMBL28800504 | 0.84 | CES1 (0.68) | ALOX5CES2CES1TDP1ALDH1A1 | |
| SCHEMBL11842226 | 0.83 | ALOX5 (0.56) | ALOX5CES2CES1PTGESTP53 | |
| SCHEMBL14893088 | 0.83 | ALOX5 (0.49) | ALOX5CES2CES1TP53SMN1; SMN2 | |
| SCHEMBL4721013 | 0.82 | CES2 (0.70) | ALOX5CES2CES1TP53CYP3A4 | |
| SCHEMBL6911469 | 0.82 | CES2 (0.75) | ALOX5CES2CES1TP53CYP3A4 | |
| SCHEMBL27935077 | 0.81 | ALOX5 (1.00) | ALOX5CES2CES1PTGESKDM4E | |
| SCHEMBL27971368 | 0.81 | ALOX5 (0.77) | ALOX5CES2CES1PTGESTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1387822-B1 | 2-[4-(2,2,-DIHALOCYCLOPROPYL)PHENOXY]-ALKANOIC ACIDS AND ESTERS THEREOF PRODUCTION PROCESS | LABORATORIO CHIMICO INT SPA (IT) | 2005-06-15 | — | — | EP | claimed |
| EP-1387822-A1 | 2-[4-(2,2,-DIHALOCYCLOPROPYL)PHENOXY]-ALKANOIC ACIDS AND ESTERS THEREOF PRODUCTION PROCESS | LABORATORIO CHIMICO INTERNAZIONALE S.p.A. (IT) | 2004-02-11 | — | — | EP | claimed |
| WO-2002090307-A1 | 2-[4-(2, 2-DIHALOCYCLOPROPYL)PHENOXY]-ALKANOIC ACIDS AND ESTERS THEREOF PRODUCTION PROCESS | LABORATORIO CHIMICO INTERNAZIONALE S.P.A. (IT) | 2002-11-14 | — | — | WO | claimed |
| CN-104059068-B | Beta-amino-carbonyl compound, preparation method, its pharmaceutical composition and application thereof | 中国科学院上海药物研究所 | 2017-02-08 | — | — | CN | disclosed |
| CN-104059068-A | Beta-amino-carbonyl compound, preparation method, its pharmaceutical composition and application thereof | SHANGHAI INST MATERIA MEDICA | 2014-09-24 | — | — | CN | disclosed |
| EP-1387822-B1 | 2-[4-(2,2,-DIHALOCYCLOPROPYL)PHENOXY]-ALKANOIC ACIDS AND ESTERS THEREOF PRODUCTION PROCESS | LABORATORIO CHIMICO INT SPA (IT) | 2005-06-15 | — | — | EP | disclosed |