Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.71 |
| ▸ | CFD | P00746 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.56 |
| ▸ | HPGD | P15428 | 4/20 | 0.56 |
| ▸ | TSHR | P16473 | 3/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.56 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.56 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.56 |
| ▸ | BLM | P54132 | 2/20 | 0.56 |
| ▸ | ESR1 | P03372 | 1/20 | 0.56 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.56 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.56 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.56 |
| ▸ | GGT1 | P19440 | 1/20 | 0.56 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9867909 | 0.85 | MAPK1 (0.62) | MAPK1CFDKDM4EALDH1A1HSD17B10 | |
| SCHEMBL9356004 | 0.84 | MAPK1 (0.60) | MAPK1CFDKDM4EALDH1A1HSD17B10 | |
| Dipyrocetyl SCHEMBL29508594 | 0.83 | MAPK1 (1.00) | MAPK1CFDKDM4EALDH1A1HSD17B10 | |
| SCHEMBL1773882 | 0.83 | MAPK1 (0.50) | MAPK1CFDKDM4EALDH1A1HSD17B10 | |
| Dipyrocetyl SCHEMBL26164 | 0.83 | MAPK1 (1.00) | MAPK1CFDKDM4EALDH1A1HSD17B10 | |
| Dipyrocetyl SCHEMBL11121474 | 0.81 | MAPK1 (0.96) | MAPK1CFDKDM4EALDH1A1HSD17B10 | |
| SCHEMBL31195949 | 0.81 | MAPK1 (0.56) | MAPK1CFDKDM4EALDH1A1HSD17B10 | |
| SCHEMBL11130469 | 0.81 | CFD (0.58) | MAPK1CFDKDM4EALDH1A1HSD17B10 | |
| SCHEMBL10944316 | 0.79 | MAPK1 (0.46) | MAPK1CFDKDM4EALDH1A1HSD17B10 | |
| SCHEMBL8667165 | 0.78 | KDM4E (0.79) | MAPK1CFDKDM4EALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118460536-A | Targeting composition | 阿布特斯生物制药公司 | 2024-08-09 | — | — | CN | disclosed |
| CN-110741087-B | Targeting composition | 阿布特斯生物制药公司 | 2024-05-14 | — | — | CN | disclosed |
| CN-114761430-A | Chimeric protein targeting PD-L1 and application thereof | 奥里尼斯生物科学股份有限公司 | 2022-07-15 | — | — | CN | disclosed |
| US-8916652-B2 | Multi-armed catechol compound blends | KENSEY NASH CORPORATION (US) | 2014-12-23 | — | — | US | disclosed |
| US-20120149849-A1 | MULTI-ARMED CATECHOL COMPOUND BLENDS | KNC NER ACQUISITION SUB, INC. (US) | 2012-06-14 | — | — | US | disclosed |
| US-8119742-B2 | Multi-armed catechol compound blends | KNC NER ACQUISITION SUB, INC. (US) | 2012-02-21 | — | — | US | disclosed |
| EP-2348835-A1 | MULTI-ARMED CATECHOL COMPOUND BLENDS | KNC NER Acquisition Sub, Inc. (US) | 2011-08-03 | — | — | EP | disclosed |
| US-20100113828-A1 | MULTI-ARMED CATECHOL COMPOUND BLENDS | NERITES CORPORATION (US) | 2010-05-06 | — | — | US | disclosed |
| WO-2010037045-A1 | MULTI-ARMED CATECHOL COMPOUND BLENDS | NERITES CORPORATION (US) | 2010-04-01 | — | — | WO | disclosed |
| US-5324804-A | Photoresist material based on polystyrenes | CIBA-GEIGY CORPORATION (US) | 1994-06-28 | — | — | US | disclosed |
| EP-0295630-A2 | Cephalosporin derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1988-12-21 | — | — | EP | disclosed |
| EP-0177596-A1 | BETA-LACTAM DERIVATIVES, PREPARATION, COMPOSITIONS CONTAINING THEM | BEECHAM GROUP PLC (GB) | 1986-04-16 | — | — | EP | disclosed |
| WO-1985004878-A1 | BETA-LACTAM DERIVATIVES, PREPARATION, COMPOSITIONS CONTAINING THEM | BEECHAM GROUP P.L.C. (GB) | 1985-11-07 | — | — | WO | disclosed |
| US-4513145-A | BACTERICIDES, URINARY TRACT DISORDERS; CEPH M INTERMEDIATES | EISAI CO., LTD. (JP) | 1985-04-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100113828-A1 | MULTI-ARMED CATECHOL COMPOUND BLENDS | COMT, HAAO, PNMT | MAPK1 3176/4885CFD 434/4885KDM4E 357/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.