Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7433769 | 0.91 | CRHR1 (0.55) | CRHR1 | |
| SCHEMBL8339677 | 0.82 | CRHR1 (0.42) | CRHR1 | |
| SCHEMBL6428085 | 0.80 | CRHR1 (0.46) | CRHR1 | |
| SCHEMBL6430284 | 0.78 | CRHR1 (0.39) | CRHR1 | |
| SCHEMBL5875479 | 0.78 | CRHR1 (0.43) | CRHR1 | |
| SCHEMBL5843980 | 0.76 | CRHR1 (0.42) | CRHR1 | |
| SCHEMBL5846016 | 0.75 | CRHR1 (0.44) | CRHR1 | |
| SCHEMBL6429241 | 0.75 | CRHR1 (0.47) | CRHR1 | |
| SCHEMBL16606729 | 0.74 | CRHR1 (0.46) | CRHR1 | |
| SCHEMBL6429755 | 0.74 | CRHR1 (0.37) | CRHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1149583-A2 | Combinations of corticotropin releasing factor antagonists and growth hormone secretagogues | Pfizer Products Inc. (US) | 2001-10-31 | — | — | EP | claimed |
| US-6844351-B1 | Corticotropin releasing factor antagonists | PFIZER INC. (US) | 2005-01-18 | — | — | US | disclosed |