Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL993053 | 0.94 | CA4 (0.60) | — | |
| Bicarbonate SCHEMBL176448 | 0.94 | CA4 (0.60) | — | |
| Bicarbonate SCHEMBL8206117 | 0.94 | — | — | |
| Bicarbonate SCHEMBL991389 | 0.94 | CA4 (0.60) | — | |
| Bicarbonate SCHEMBL77648 | 0.94 | — | — | |
| Bicarbonate SCHEMBL11275439 | 0.94 | CA4 (0.60) | — | |
| Bicarbonate SCHEMBL11693424 | 0.94 | CA4 (0.60) | — | |
| Bicarbonate SCHEMBL17477711 | 0.94 | CA4 (0.60) | — | |
| Bicarbonate SCHEMBL8206114 | 0.94 | — | — | |
| Bicarbonate SCHEMBL15021043 | 0.94 | CA4 (0.60) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220054589-A1 | Compositions Comprising Antimicrobial Peptides | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION | 2022-02-24 | — | — | US | claimed |
| US-5688904-A | USING EFFLUENT OF AN IMMOBILIZED CELL OR ENZYME AS CATALYST | CALWOOD CHEMICAL INDUSTRIES INC. (US) | 1997-11-18 | — | — | US | claimed |
| US-5610264-A | Continuous process for polyaspartic acid synthesis | CALWOOD CHEMICAL INDUSTRIES, INC. (US) | 1997-03-11 | — | — | US | claimed |
| US-6958144-B2 | Methods of whitening teeth | BRITESMILE DEVELOPMENT, INC. (US) | 2005-10-25 | — | — | US | disclosed |
| EP-0861274-A4 | CONTINUOUS PROCESS FOR POLYASPARTIC ACID SYNTHESIS | CALWOOD CHEM IND INC (US) | 1998-10-28 | — | — | EP | disclosed |
| EP-0861274-A1 | CONTINUOUS PROCESS FOR POLYASPARTIC ACID SYNTHESIS | Calwood Chemical Industries, Inc. (US) | 1998-09-02 | — | — | EP | disclosed |
| US-5688904-A | USING EFFLUENT OF AN IMMOBILIZED CELL OR ENZYME AS CATALYST | CALWOOD CHEMICAL INDUSTRIES INC. (US) | 1997-11-18 | — | — | US | disclosed |
| WO-1997018249-A1 | CONTINUOUS PROCESS FOR POLYASPARTIC ACID SYNTHESIS | CALWOOD CHEMICAL INDUSTRIES, INC. (US) | 1997-05-22 | — | — | WO | disclosed |
| US-5610264-A | Continuous process for polyaspartic acid synthesis | CALWOOD CHEMICAL INDUSTRIES, INC. (US) | 1997-03-11 | — | — | US | disclosed |
| US-4708805-A | SOLUTION OF CITRIC ACID, A POLYCARATIC ACID AND AN ALKYLENEPOLYAMINOPOLYCARBOXYLIC ACID | CORPEX TECHNOLOGIES, INC. | 1987-11-24 | — | — | US | disclosed |