Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 18/20 | 0.53 |
| ▸ | RARG | P13631 | 15/20 | 0.53 |
| ▸ | RARA | P10276 | 15/20 | 0.53 |
| ▸ | RXRA | P19793 | 1/20 | 0.49 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6427912 | 0.97 | RARB (0.53) | RARBRARGRARARXRANR2E1 | |
| SCHEMBL6259688 | 0.88 | RARB (0.65) | RARBRARGRARARXRANR2E1 | |
| SCHEMBL6259689 | 0.88 | RARB (0.65) | RARBRARGRARARXRANR2E1 | |
| SCHEMBL6428468 | 0.88 | RARB (0.51) | RARBRARGRARARXRANR2E1 | |
| SCHEMBL6428467 | 0.88 | RARA (0.57) | RARBRARGRARARXRANR2E1 | |
| SCHEMBL6259693 | 0.86 | RARB (0.65) | RARBRARGRARARXRANR2E1 | |
| SCHEMBL6427908 | 0.84 | RARB (0.50) | RARBRARGRARARXRANR2E1 | |
| SCHEMBL6427871 | 0.82 | RARB (0.49) | RARBRARGRARARXRANR2E1 | |
| SCHEMBL6261626 | 0.82 | RARB (0.49) | RARBRARGRARARXRANR2E1 | |
| SCHEMBL6262012 | 0.82 | RARB (0.51) | RARBRARGRARARXRANR2E1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6906057-B1 | Methods for modulating FXR receptor activity | ALLERGAN, INC. (US) | 2005-06-14 | — | — | US | disclosed |