Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARA | P10276 | 18/20 | 0.57 |
| ▸ | RARB | P10826 | 17/20 | 0.57 |
| ▸ | RARG | P13631 | 17/20 | 0.57 |
| ▸ | RXRA | P19793 | 1/20 | 0.57 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6428468 | 0.93 | RARB (0.51) | RARARARBRARGRXRANR2E1 | |
| SCHEMBL6427912 | 0.91 | RARB (0.53) | RARARARBRARGRXRANR2E1 | |
| SCHEMBL6428264 | 0.88 | RARB (0.53) | RARARARBRARGRXRANR2E1 | |
| SCHEMBL6262565 | 0.87 | RARA (0.72) | RARARARBRARGRXRANR2E1 | |
| SCHEMBL6262562 | 0.85 | RARA (0.75) | RARARARBRARGRXRANR2E1 | |
| SCHEMBL6264495 | 0.82 | RARA (0.55) | RARARARBRARGRXRANR2E1 | |
| SCHEMBL6428464 | 0.81 | RARB (0.58) | RARARARBRARGRXRANR2E1 | |
| SCHEMBL6259669 | 0.80 | RARB (0.63) | RARARARBRARGRXRANR2E1 | |
| SCHEMBL6258858 | 0.80 | RARA (0.58) | RARARARBRARGRXRANR2E1 | |
| SCHEMBL6428636 | 0.79 | RARG (0.54) | RARARARBRARGRXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6906057-B1 | Methods for modulating FXR receptor activity | ALLERGAN, INC. (US) | 2005-06-14 | — | — | US | disclosed |