Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 3/20 | 0.50 |
| ▸ | ESR1 | P03372 | 3/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | AR | P10275 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | HTR6 | P50406 | 1/20 | 0.46 |
| ▸ | ESRRG | P62508 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.39 |
| ▸ | CHKA | P35790 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2815903 | 0.85 | MAPT (0.52) | KIF11ESR1ESR2CYP3A4TSHR | |
| SCHEMBL27526789 | 0.84 | KIF11 (0.52) | KIF11CYP3A4TSHRLMNAMAPT | |
| SCHEMBL19157934 | 0.82 | SMN1; SMN2 (0.52) | KIF11CYP3A4HPGDLMNAMAPT | |
| SCHEMBL65312 | 0.81 | KIF11 (0.71) | KIF11TSHRHPGDLMNAMAPT | |
| SCHEMBL820736 | 0.81 | KIF11 (0.71) | KIF11TSHRHPGDLMNAMAPT | |
| Lithium SCHEMBL29576172 | 0.79 | KIF11 (0.68) | KIF11TSHRHPGDLMNAMAPT | |
| SCHEMBL29245411 | 0.79 | KIF11 (0.68) | KIF11TSHRHPGDLMNAMAPT | |
| SCHEMBL20137330 | 0.79 | KIF11 (0.68) | KIF11TSHRHPGDLMNAMAPT | |
| SCHEMBL28443995 | 0.79 | KIF11 (0.68) | KIF11TSHRHPGDLMNAMAPT | |
| Hydrochloric Acid SCHEMBL15140525 | 0.79 | KIF11 (0.68) | KIF11TSHRHPGDLMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6921824-B1 | Ruthenium dimeric complexes suitable as antimetastatic and antineoplastic agents | SIGEA S.R.L. (IT) | 2005-07-26 | — | — | US | claimed |
| EP-1185540-B1 | RUTHENIUM DIMERIC COMPLEXES SUITABLE AS ANTIMETASTATIC AND ANTINEOPLASTIC AGENTS | SIGEA SRL (IT) | 2003-08-27 | — | — | EP | claimed |
| EP-1185540-A1 | RUTHENIUM DIMERIC COMPLEXES SUITABLE AS ANTIMETASTATIC AND ANTINEOPLASTIC AGENTS | Sigea S.r.l. (IT) | 2002-03-13 | — | — | EP | claimed |
| WO-2000063218-A1 | RUTHENIUM DIMERIC COMPLEXES SUITABLE AS ANTIMETASTATIC AND ANTINEOPLASTIC AGENTS | SIGEA S.R.L. (IT) | 2000-10-26 | — | — | WO | claimed |
| EP-1392707-A2 | NEW ANIONIC AND NEUTRAL COMPLEXES OF RUTHENIUM (II) WITH NITROGEN OXIDE | Sigea S.R.L. (IT) | 2004-03-03 | — | — | EP | disclosed |
| WO-2002076998-A2 | NEW ANIONIC AND NEUTRAL COMPLEXES OF RUTHENIUM (II) WITH NITROGEN OXIDE | SIGEA S.R.L. (IT) | 2002-10-03 | — | — | WO | disclosed |