Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 4/20 | 0.71 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 6/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | TYR | P14679 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.41 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL65312 | 1.00 | KIF11 (0.71) | KIF11TSHRLMNAMAPTHTT | |
| SCHEMBL27528935 | 0.97 | KIF11 (0.68) | KIF11TSHRLMNAMAPTHTT | |
| SCHEMBL29245411 | 0.97 | KIF11 (0.68) | KIF11TSHRLMNAMAPTHTT | |
| SCHEMBL28443995 | 0.97 | KIF11 (0.68) | KIF11TSHRLMNAMAPTHTT | |
| SCHEMBL20137330 | 0.97 | KIF11 (0.68) | KIF11TSHRLMNAMAPTHTT | |
| Lithium SCHEMBL29576172 | 0.97 | KIF11 (0.68) | KIF11TSHRLMNAMAPTHTT | |
| Ethane SCHEMBL3064994 | 0.97 | KIF11 (0.68) | KIF11TSHRLMNAMAPTHTT | |
| Hydrochloric Acid SCHEMBL15140525 | 0.97 | KIF11 (0.68) | KIF11TSHRLMNAMAPTHTT | |
| SCHEMBL16694367 | 0.92 | KIF11 (0.86) | KIF11TSHRLMNAMAPTHTT | |
| SCHEMBL18866678 | 0.89 | KIF11 (0.67) | KIF11TSHRLMNAMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115594701-A | Preparation method of allyl-substituted aryl borate organic boron compound | 青海师范大学（CN） | 2023-01-13 | — | — | CN | claimed |
| CN-115448941-A | Preparation method of allyl substituted aryl organosilicon compound | 青海师范大学 | 2022-12-09 | — | — | CN | claimed |
| US-20250026759-A1 | TETRAHYDROQUINAZOLINE DERIVATIVES AS SELECTIVE CYTOTOXIC AGENTS | MERCK SHARP & DOHME LLC (US) | 2025-01-23 | — | — | US | disclosed |
| CN-117813302-A | Substituted tetrahydrofuran-2-carboxamides as sodium channel modulators | 沃泰克斯药物股份有限公司 | 2024-04-02 | — | — | CN | disclosed |
| US-8598349-B2 | Method for manufacturing conjugated aromatic compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-12-03 | — | — | US | disclosed |
| US-20110275859-A1 | METHOD FOR MANUFACTURING CONJUGATED AROMATIC COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED | 2011-11-10 | — | — | US | disclosed |
| WO-2010048920-A1 | RADIATION-EMITTING DEVICE | OSRAM OPTO SEMICONDUCTORS GMBH (DE) | 2010-05-06 | — | — | WO | disclosed |
| EP-1904441-A4 | PROCESS FOR PRODUCING CYANO SUBSTITUTED ARENE BORANES AND COMPOUNDS | UNIV MICHIGAN STATE (US) | 2009-05-13 | — | — | EP | disclosed |
| EP-1904441-A1 | PROCESS FOR PRODUCING CYANO SUBSTITUTED ARENE BORANES AND COMPOUNDS | MICHIGAN STATE UNIVERSITY (US) | 2008-04-02 | — | — | EP | disclosed |
| WO-2006135705-A1 | PROCESS FOR PRODUCING CYANO SUBSTITUTED ARENE BORANES AND COMPOUNDS | MICHIGAN STATE UNIVERSITY (US) | 2006-12-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110275859-A1 | METHOD FOR MANUFACTURING CONJUGATED AROMATIC COMPOUND | C9, H1-10, CYP1A1 | KIF11 95/4885TSHR 185/4885LMNA 1269/4885 |
| US-20250026759-A1 | TETRAHYDROQUINAZOLINE DERIVATIVES AS SELECTIVE CYTOTOXIC AGENTS | ACIN1, REV1, NFATC1 | KIF11 3314/4885TSHR 4805/4885LMNA 3610/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.