Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 3/20 | 0.40 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.40 |
| ▸ | SRC | P12931 | 2/20 | 0.38 |
| ▸ | ELANE | P08246 | 2/20 | 0.35 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | IGFBP3 | P17936 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6428320 | 0.90 | SRC (0.36) | AKR1C3AKR1C2SRCELANELMNA | |
| SCHEMBL6423421 | 0.89 | AKR1C3 (0.39) | AKR1C3AKR1C2SRC | |
| SCHEMBL6425546 | 0.88 | MEN1 (0.34) | AKR1C3AKR1C2SRCIGFBP3KMT2A | |
| SCHEMBL5554437 | 0.88 | SRC (0.40) | AKR1C3AKR1C2SRCELANEPLA2G7 | |
| SCHEMBL5554442 | 0.88 | SRC (0.40) | AKR1C3AKR1C2SRCELANEPLA2G7 | |
| SCHEMBL5550631 | 0.88 | SRC (0.40) | AKR1C3AKR1C2SRCELANEPLA2G7 | |
| SCHEMBL6425023 | 0.87 | AKR1C3 (0.45) | AKR1C3AKR1C2ELANEPLA2G7LMNA | |
| SCHEMBL6423760 | 0.87 | AKR1C3 (0.39) | AKR1C3AKR1C2SRCELANEPLA2G7 | |
| SCHEMBL6425556 | 0.87 | BCL2 (0.40) | AKR1C3AKR1C2SRCLMNA | |
| SCHEMBL6423638 | 0.85 | AKR1C3 (0.40) | AKR1C3AKR1C2SRCELANEPLA2G7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050234244-A1 | Synthesis of COX-2 and FAAH inhibitors | IRONWOOD PHARMACEUTICALS, INC. | 2005-10-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050234244-A1 | Synthesis of COX-2 and FAAH inhibitors | FAAH2, FAAH, PTGES2 | AKR1C3 577/4885AKR1C2 563/4885SRC 3467/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.