SCHEMBL6428487

SCHEMBL6428487

C=C(C(=O)O)C(Cl)C(Cl)(Cl)Cl

nearest known ligand 0.32

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.32
ALDH1A1 P00352 1/20 0.32
TP53 P04637 1/20 0.32
TSHR P16473 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7869609 0.74 LMNA (0.33) LMNAALDH1A1TP53TSHR
SCHEMBL11593914 0.72 ALDH1A1 (0.35) LMNAALDH1A1TP53TSHR
SCHEMBL11593917 0.72 ALDH1A1 (0.35) LMNAALDH1A1TP53TSHR
SCHEMBL7868058 0.72 ALDH1A1 (0.33) ALDH1A1TP53TSHR
SCHEMBL10704427 0.71
SCHEMBL7692501 0.71
SCHEMBL7866419 0.67
SCHEMBL7866427 0.67 CYP2C19 (0.30) LMNA
SCHEMBL2770120 0.67 LMNA (0.35) LMNAALDH1A1
SCHEMBL233607 0.67 LMNA (0.42) LMNAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6341190-B1 Organic optical components and preparation thereof EPIGEM LIMITED (GB) 2002-01-22 US claimed
EP-1124786-A1 PROCESS FOR THE PREPARATION AND USES OF DERIVATIVES OF ESTERS OF ALPHA-METHYLENE- BETA-HYDROXY ACIDS Uniroyal Chemical Company, Inc. (US) 2001-08-22 EP claimed
EP-0722387-B1 ORGANIC OPTICAL COMPONENTS AND PREPARATION THEREOF EPIGEM LIMITED (GB) 2000-09-06 EP claimed
WO-2000027793-A1 PROCESS FOR THE PREPARATION AND USES OF DERIVATIVES OF ESTERS OF ALPHA- METHYLENE- BETA- HYDROXY ACIDS UNIROYAL CHEMICAL COMPANY, INC. (US) 2000-05-18 WO claimed
US-5985084-A Organic optical components and preparation thereof EPIGEM LTD. (GB) 1999-11-16 US claimed
EP-0722387-A1 ORGANIC OPTICAL COMPONENTS AND PREPARATION THEREOF Epigem Limited (GB) 1996-07-24 EP claimed
WO-1995009726-A1 ORGANIC OPTICAL COMPONENTS AND PREPARATION THEREOF EPIGEM LTD (GB) 1995-04-13 WO claimed
US-11912860-B2 Highly loaded inorganic filled organic resin systems CORNING INCORPORATED (US) 2024-02-27 US disclosed
US-11674030-B2 Highly loaded inorganic filled aqueous resin systems CORNING INCORPORATED (US) 2023-06-13 US disclosed
US-20210047510-A1 HIGHLY LOADED INORGANIC FILLED ORGANIC RESIN SYSTEMS CORNING INCORPORATED 2021-02-18 US disclosed
US-20200299500-A1 HIGHLY LOADED INORGANIC FILLED AQUEOUS RESIN SYSTEMS CORNING INCORPORATED 2020-09-24 US disclosed
WO-2019191564-A1 HIGHLY LOADED INORGANIC FILLED ORGANIC RESIN SYSTEMS CORNING INCORPORATED (US) 2019-10-03 WO disclosed
EP-0937280-B1 MULTIFUNCTIONAL MICROSTRUCTURES AND PREPARATION THEREOF EPIGEM LTD (GB) 2013-05-29 EP disclosed
EP-0722387-B1 ORGANIC OPTICAL COMPONENTS AND PREPARATION THEREOF EPIGEM LIMITED (GB) 2000-09-06 EP disclosed
WO-2000027793-A1 PROCESS FOR THE PREPARATION AND USES OF DERIVATIVES OF ESTERS OF ALPHA- METHYLENE- BETA- HYDROXY ACIDS UNIROYAL CHEMICAL COMPANY, INC. (US) 2000-05-18 WO disclosed
US-5985084-A Organic optical components and preparation thereof EPIGEM LTD. (GB) 1999-11-16 US disclosed
EP-0824713-A2 MICRO RELIEF ELEMENT AND PREPARATION THEREOF Epigem Limited (GB) 1998-02-25 EP disclosed
WO-1996035971-A2 MICRO RELIEF ELEMENT AND PREPARATION THEREOF EPIGEM LIMITED (GB) 1996-11-14 WO disclosed
EP-0722387-A1 ORGANIC OPTICAL COMPONENTS AND PREPARATION THEREOF Epigem Limited (GB) 1996-07-24 EP disclosed
WO-1995009726-A1 ORGANIC OPTICAL COMPONENTS AND PREPARATION THEREOF EPIGEM LTD (GB) 1995-04-13 WO disclosed