Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.35 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.33 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.31 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.31 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.31 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3142793 | 0.83 | TDP1 (0.48) | TDP1SLC22A6FOLH1SMN1; SMN2GABRR1 | |
| SCHEMBL10932851 | 0.82 | FOLH1 (0.46) | TDP1SLC22A6FOLH1LMNA | |
| SCHEMBL28221122 | 0.80 | FOLH1 (0.45) | TDP1SLC22A6FOLH1 | |
| SCHEMBL28220537 | 0.80 | FOLH1 (0.45) | TDP1SLC22A6FOLH1 | |
| SCHEMBL11545034 | 0.80 | HDAC1 (0.44) | TDP1SLC22A6GPR84 | |
| SCHEMBL9402802 | 0.80 | FOLH1 (0.45) | TDP1SLC22A6FOLH1 | |
| SCHEMBL270921 | 0.80 | THRB (0.32) | — | |
| SCHEMBL6838776 | 0.78 | THRB (0.30) | — | |
| SCHEMBL10590558 | 0.77 | GPR84 (0.46) | TDP1GPR84FFAR1FFAR4 | |
| SCHEMBL271680 | 0.75 | THRB (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6916481-B1 | Active-substance vector multiparticulate system, production and use thereof | Chimie, Rhodia (FR) | 2005-07-12 | — | — | US | disclosed |
| US-6300306-B1 | TREATING HARD SURFACES, POLYOXYALKYLENE UNITS AND SULFONATEDPOLYAMIDES AND SULFONATED POLYFUNCTIONAL UNITS AND BINDING GROUPS WITH ESTER | RHODIA CHIMIE (FR) | 2001-10-09 | — | — | US | disclosed |
| EP-0136899-B1 | AMORPHOUS SULFOPOLYESTERS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1989-04-19 | — | — | EP | disclosed |
| EP-0136899-A2 | Amorphous sulfopolyesters | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1985-04-10 | — | — | EP | disclosed |
| US-4480085-A | Amorphous sulfopolyesters | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1984-10-30 | — | — | US | disclosed |